Spectral and Temporal Processing in Rat Posterior Auditory Cortex

Overview

Journal Cereb Cortex

Publisher Oxford University Press

Specialty Neurology

Date 2007 Jul 7

PMID 17615251

Citations 20

Authors

Pritesh K Pandya

Daniel L Rathbun

Raluca Moucha

Navzer D Engineer

Michael P Kilgard

Affiliations

Soon will be listed here.

Abstract

The rat auditory cortex is divided anatomically into several areas, but little is known about the functional differences in information processing between these areas. To determine the filter properties of rat posterior auditory field (PAF) neurons, we compared neurophysiological responses to simple tones, frequency modulated (FM) sweeps, and amplitude modulated noise and tones with responses of primary auditory cortex (A1) neurons. PAF neurons have excitatory receptive fields that are on average 65% broader than A1 neurons. The broader receptive fields of PAF neurons result in responses to narrow and broadband inputs that are stronger than A1. In contrast to A1, we found little evidence for an orderly topographic gradient in PAF based on frequency. These neurons exhibit latencies that are twice as long as A1. In response to modulated tones and noise, PAF neurons adapt to repeated stimuli at significantly slower rates. Unlike A1, neurons in PAF rarely exhibit facilitation to rapidly repeated sounds. Neurons in PAF do not exhibit strong selectivity for rate or direction of narrowband one octave FM sweeps. These results indicate that PAF, like nonprimary visual fields, processes sensory information on larger spectral and longer temporal scales than primary cortex.

Citing Articles

Parietal Cortex Is Required for the Integration of Acoustic Evidence.

Yao J, Gimoto J, Constantinople C, Sanes D Curr Biol. 2020; 30(17):3293-3303.e4.

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Auditory steady-state responses in primary and non-primary regions of the auditory cortex in neonatal ventral hippocampal lesion rats.

Li S, Ma L, Wang Y, Wang X, Li Y, Qin L PLoS One. 2018; 13(2):e0192103.

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Topographic Distribution of Stimulus-Specific Adaptation across Auditory Cortical Fields in the Anesthetized Rat.

Nieto-Diego J, Malmierca M PLoS Biol. 2016; 14(3):e1002397.

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Speech training alters consonant and vowel responses in multiple auditory cortex fields.

Engineer C, Rahebi K, Buell E, Fink M, Kilgard M Behav Brain Res. 2015; 287:256-64.

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Speech sound processing deficits and training-induced neural plasticity in rats with dyslexia gene knockdown.

Centanni T, Chen F, Booker A, Engineer C, Sloan A, Rennaker R PLoS One. 2014; 9(5):e98439.

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