Rapid Viral Quasispecies Evolution: Implications for Vaccine and Drug Strategies

Overview

Journal Mol Med Today

Specialties General Medicine
Molecular Biology

Date 1995 Aug 1

PMID 17607887

Citations 15

Authors

I S Novella

E Domingo

J J Holland

Affiliations

Soon will be listed here.

Abstract

High mutation rates occurring during replication allow RNA viruses to evolve rapidly and adapt continuously to new environments. This poses an enormous challenge to vaccine and drug development which, to be effective, must consider RNA virus variability and follow approaches that minimize the probability of escape or resistant mutants arising.

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