Personality, Stress, Smoking, and Genetic Predisposition As Synergistic Risk Factors for Cancer and Coronary Heart Disease

Overview

Journal Integr Physiol Behav Sci

Specialty Social Sciences

Date 1991 Oct 1

PMID 1760380

Citations 11

Authors

H J Eysenck

R Grossarth-Maticek

B Everitt

Affiliations

Soon will be listed here.

Abstract

Risk factors for cancer have been found in the past to act synergistically in a number of studies. However, these studies were not always designed to test the hypothesis of synergism, and have sometimes failed to equate for important variables, which might influence the results. The present study tests the hypothesis that psychosocial variables and physical ones (personality/stress, smoking, and genetic predisposition) interact in a synergistic fashion in the causation of lung cancer and coronary heart disease (CHD).

Citing Articles

The prevalence of anxiety symptoms/disorders in cancer patients: a meta-analysis.

Amiri S Front Psychiatry. 2024; 15:1422540.

PMID: 39619339 PMC: 11605443. DOI: 10.3389/fpsyt.2024.1422540.

Retraction Note to: Personality, Stress, Smoking, and Genetic Predisposition as Synergistic Risk Factors for Cancer and Coronary Heart Disease.

Eysenck H, Grossarth-Maticek R, Everitt B Integr Psychol Behav Sci. 2021; 58(4):2066-2067.

PMID: 33846947 DOI: 10.1007/s12124-021-09602-2.

Role of personality in tobacco smoking behavior in corporate sector: A cross-sectional study.

Kulkarni P, Parkar S, Kate N, Ninawe K, Limbachiya R Ind Psychiatry J. 2018; 27(1):103-109.

PMID: 30416300 PMC: 6198598. DOI: 10.4103/ipj.ipj_46_16.

Perceived stress level and risk of cancer incidence in a Japanese population: the Japan Public Health Center (JPHC)-based Prospective Study.

Song H, Saito E, Sawada N, Abe S, Hidaka A, Shimazu T Sci Rep. 2017; 7(1):12964.

PMID: 29021585 PMC: 5636815. DOI: 10.1038/s41598-017-13362-8.

Personality and longevity: knowns, unknowns, and implications for public health and personalized medicine.

Chapman B, Roberts B, Duberstein P J Aging Res. 2011; 2011:759170.

PMID: 21766032 PMC: 3134197. DOI: 10.4061/2011/759170.

References

Rothman K . The estimation of synergy or antagonism. Am J Epidemiol. 1976; 103(5):506-11. DOI: 10.1093/oxfordjournals.aje.a112252. View

Grossarth-Maticek R, Eysenck H . Personality, smoking, and alcohol as synergistic risk factors for cancer of the mouth and pharynx. Psychol Rep. 1990; 67(3 Pt 1):1024-6. DOI: 10.2466/pr0.1990.67.3.1024. View

Grossarth-Maticek R, Eysenck H . Personality, stress and disease: description and validation of a new inventory. Psychol Rep. 1990; 66(2):355-73. DOI: 10.2466/pr0.1990.66.2.355. View

Saracci R . The interactions of tobacco smoking and other agents in cancer etiology. Epidemiol Rev. 1987; 9:175-93. DOI: 10.1093/oxfordjournals.epirev.a036301. View

Grossarth-Maticek R . Synergetic effects of cigarette smoking, systolic blood pressure, and psychosocial risk factors for lung cancer, cardiac infarct and apoplexy cerebri. Psychother Psychosom. 1980; 34(4):267-72. DOI: 10.1159/000287468. View

Grossarth-Maticek R, Eysenck H . Creative novation behaviour therapy as a prophylactic treatment for cancer and coronary heart disease: Part I--Description of treatment. Behav Res Ther. 1991; 29(1):1-16. DOI: 10.1016/s0005-7967(09)80002-8. View

Everitt B, Smith A . Interactions in contingency tables: a brief discussion of alternative definitions. Psychol Med. 1979; 9(3):581-3. DOI: 10.1017/s0033291700032141. View

Perkins K . Use of terms to describe results: "additive" vs. "synergistic". Psychophysiology. 1987; 24(6):719-21. DOI: 10.1111/j.1469-8986.1987.tb00356.x. View

Kannel W, Neaton J, Wentworth D, Thomas H, Stamler J, Hulley S . Overall and coronary heart disease mortality rates in relation to major risk factors in 325,348 men screened for the MRFIT. Multiple Risk Factor Intervention Trial. Am Heart J. 1986; 112(4):825-36. DOI: 10.1016/0002-8703(86)90481-3. View

10.

Tennant C, Bebbington P . The social causation of depression: a critique of the work of Brown and his colleagues. Psychol Med. 1978; 8(4):565-75. DOI: 10.1017/s003329170001878x. View

11.

Brown G, Harris T . Social origins of depression: a reply. Psychol Med. 1978; 8(4):577-88. DOI: 10.1017/s0033291700018791. View

12.

Walker A . Proportion of disease attributable to the combined effect of two factors. Int J Epidemiol. 1981; 10(1):81-5. DOI: 10.1093/ije/10.1.81. View

13.

Koopman J . Interaction between discrete causes. Am J Epidemiol. 1981; 113(6):716-24. DOI: 10.1093/oxfordjournals.aje.a113153. View

14.

Saracci R . Interaction and synergism. Am J Epidemiol. 1980; 112(4):465-6. DOI: 10.1093/oxfordjournals.aje.a113014. View

15.

Rothman K . Synergy and antagonism in cause-effect relationships. Am J Epidemiol. 1974; 99(6):385-8. DOI: 10.1093/oxfordjournals.aje.a121626. View

16.

Grossarth-Maticek R, Vetter H, Frentzel-Beyme R, Heller W . Precursor lesions of the GI tract and psychosocial risk factors for prediction and prevention of gastric cancer. Cancer Detect Prev. 1988; 13(1):23-9. View

17.

Cornfield J . Joint dependence of risk of coronary heart disease on serum cholesterol and systolic blood pressure: a discriminant function analysis. Fed Proc. 1962; 21(4)Pt 2:58-61. View

18.

GRIZZLE J, Starmer C, Koch G . Analysis of categorical data by linear models. Biometrics. 1969; 25(3):489-504. View

19.

Grossarth-Maticek R, Eysenck H, Gallasch G, Vetter H, Frentzel-Beyme R . Changes in degree of sclerosis as a function of prophylactic treatment in cancer-prone and CHD-prone probands. Behav Res Ther. 1991; 29(4):343-51. DOI: 10.1016/0005-7967(91)90070-j. View

20.

Eysenck H, Grossarth-Maticek R . Creative novation behaviour therapy as a prophylactic treatment for cancer and coronary heart disease: Part II--Effects of treatment. Behav Res Ther. 1991; 29(1):17-31. DOI: 10.1016/s0005-7967(09)80003-x. View