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The Impact of Splenectomy on Outcomes After Distal and Total Pancreatectomy

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Publisher Biomed Central
Date 2007 Jun 5
PMID 17543130
Citations 11
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Abstract

Background: Several authors advocate spleen preserving distal pancreatectomy, because of the increased complication rate after splenectomy.

Methods: Postoperative complications and survival after distal and total pancreatectomy, were recorded and retrospectively analyzed according to spleen preservation. Patients, who underwent distal and total pancreatectomy without histologically proven adenocarcinoma, or extrapancreatic disease, were included in the cohort which was divided into splenectomy and no splenectomy groups. Statistical analysis was performed using Fisher's test.

Results: The study group consisted of 62 patients who underwent distal and total pancreatectomy between 26/11/1987 to 6/1/2006. Splenectomy was performed in 35 out of 62 patients (56.5%), distal pancreatectomy was performed in 49 out of 62 patients (79%). Morbidity rate was 28.6% in splenectomy group and 14.8% in the no splenectomy group (p = 0.235), while 30 days mortality rate was 2.9%; one patient died in the splenectomy group (p = 1).

Conclusion: Spleen-preservation did not influence the outcomes after distal and total pancreatectomy in our series.

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References
1.
Lillemoe K, Kaushal S, Cameron J, Sohn T, Pitt H, Yeo C . Distal pancreatectomy: indications and outcomes in 235 patients. Ann Surg. 1999; 229(5):693-8; discussion 698-700. PMC: 1420814. DOI: 10.1097/00000658-199905000-00012. View

2.
Beger H, Buchler M, Bittner R, Oettinger W, Roscher R . Duodenum-preserving resection of the head of the pancreas in severe chronic pancreatitis. Early and late results. Ann Surg. 1989; 209(3):273-8. PMC: 1493931. DOI: 10.1097/00000658-198903000-00004. View

3.
Balcom 4th J, Rattner D, Warshaw A, Chang Y, Fernandez-Del Castillo C . Ten-year experience with 733 pancreatic resections: changing indications, older patients, and decreasing length of hospitalization. Arch Surg. 2001; 136(4):391-8. DOI: 10.1001/archsurg.136.4.391. View

4.
Holdsworth R, Irving A, Cuschieri A . Postsplenectomy sepsis and its mortality rate: actual versus perceived risks. Br J Surg. 1991; 78(9):1031-8. DOI: 10.1002/bjs.1800780904. View

5.
Suc B, Msika S, Fingerhut A, Fourtanier G, Hay J, Holmieres F . Temporary fibrin glue occlusion of the main pancreatic duct in the prevention of intra-abdominal complications after pancreatic resection: prospective randomized trial. Ann Surg. 2002; 237(1):57-65. PMC: 1513966. DOI: 10.1097/00000658-200301000-00009. View