Perfusion-sensitive MRI of Pilocytic Astrocytomas: Initial Results

Overview

Journal Neuroradiology

Specialties Neurology
Radiology

Date 2007 May 29

PMID 17530237

Citations 14

Authors

Sylvie D Grand

Stephane Kremer

Irene M Tropres

Dominique M Hoffmann

Stephan J Chabardes

Virginie Lefournier

Francois R Berger

Caroline Pasteris

Alexandre Krainik

Basile M Pasquier

Michel Peoch

Jean Francois Le Bas

Affiliations

Soon will be listed here.

Abstract

Purpose: To present the imaging and perfusion data obtained in nine patients with pilocytic astrocytomas (PA) and to discuss the original functional issues of this technique.

Method: Nine patients with pathologically proven PA underwent conventional and perfusion MR imaging. Various areas of relative cerebral blood volume (rCBV) within the tumors were obtained. The maximum rCBV ratios were identified and considered as representative of the tumor. The results were compared with the pathological findings.

Results: In all patients, rCBV was <1.5 (mean 1) and the signal intensity curve overshot the baseline.

Conclusion: PA tend to have low rCBV values and a first-pass curve that crosses the baseline. These characteristics may be explained by the histological profile of the tumoral vascularity and are of relevance in the identification of these rare tumors.

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