Incidence of Helicobacter Pylori Infection and Gastric Cancer : an 8-year Hospital Based Study
Overview
Affiliations
Aim: To observe the tendency of decreased prevalence of H pylori infection in a 14 year-period and observe the prevalence of intestinal metaplasia and gastric cancer.
Methods: All patients who were diagnosed with dyspepsia and underwent esophagogastroduodenoscopy in Cikini hospital Jakarta from January 1998 until December 2005 were evaluated. We evaluated the histopathologic result of H pylori, the presence of intestinal metaplasia and gastric cancer. Data was grouped for 1 year period of time and was presented descriptively.
Results: Decreased prevalence of H. Pylori infection was found, from 12.8% in 1998, 12.4% in 1999, 14.7% in 2000, 9.6% in 2001, 11.9 % in 2002, 3.8% in 2003, 2.3% in 2004, 2.9% in 2005. Intestinal metaplasia was 4.7% in 1998, 3.2% in 1999, 3.1% in 2000, 2.3 % in 2001, 7.6% in 2002, 8.3% in year 2003, 6.5% in 2004, 7.1% in 2005. Prevalence of gastric cancer was 2.2% in 1998, 0.25% in 1999, 1.1% in 2000, 1.1% in 2001, 1.1% in 2002, 1.8% in 2003, 1.7% in 2004, 3.9% in 2005.
Conclusion: There was decreased prevalence of H pylori infection in 8 year-period but there was no decreased prevalence of intestinal metaplasia and gastric cancer found.
AGA Technical Review on Gastric Intestinal Metaplasia-Epidemiology and Risk Factors.
Altayar O, Davitkov P, Shah S, Gawron A, Morgan D, Turner K Gastroenterology. 2019; 158(3):732-744.e16.
PMID: 31816301 PMC: 7425600. DOI: 10.1053/j.gastro.2019.12.002.
Goto Y, Syam A, Darnindro N, Hapsari F Asian Pac J Cancer Prev. 2016; 17(10):4747-4753.
PMID: 27893207 PMC: 5454627. DOI: 10.22034/apjcp.2016.17.10.4747.
Syam A, Miftahussurur M, Makmun D, Nusi I, Zain L, Zulkhairi PLoS One. 2015; 10(11):e0140186.
PMID: 26599790 PMC: 4658100. DOI: 10.1371/journal.pone.0140186.
Miftahussurur M, Tuda J, Suzuki R, Kido Y, Kawamoto F, Matsuda M Gut Pathog. 2014; 6(1):42.
PMID: 25299127 PMC: 4189669. DOI: 10.1186/s13099-014-0042-0.
Miftahussurur M, Shiota S, Suzuki R, Matsuda M, Uchida T, Kido Y Epidemiol Infect. 2014; 143(5):986-96.
PMID: 25034254 PMC: 9507110. DOI: 10.1017/S095026881400154X.