Gold-catalyzed Efficient Preparation of Linear Alpha-iodoenones from Propargylic Acetates

Overview

Journal Org Lett

Publisher American Chemical Society

Specialties Biochemistry
Chemistry

Date 2007 May 1

PMID 17465561

Citations 19

Authors

Meng Yu

Guozhu Zhang

Liming Zhang

Affiliations

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Abstract

Only 2 mol % of Au(PPh3)NTf2 is needed to convert readily accessible propargylic acetates into versatile linear alpha-iodoenones in good to excellent yields. This reaction is easy to execute and has broad substrate scope. Good to excellent Z-selectivities are observed in the cases of aliphatic propargylic acetates derived from aldehydes.

Citing Articles

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Homogeneous Gold-Catalyzed Oxidation Reactions.

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