Clinicopathological Characteristics of Esophageal Squamous Papillomas in Japanese Patients--with Comparison of Findings from Western Countries

Overview

Journal Acta Histochem Cytochem

Specialty Biochemistry

Date 2007 Apr 27

PMID 17460769

Citations 21

Authors

Kuniko Takeshita

Shin-Ichi Murata

Shoji Mitsufuji

Naoki Wakabayashi

Keisho Kataoka

Yasunari Tsuchihashi

Takeshi Okanoue

Affiliations

Soon will be listed here.

Abstract

To clarify the characteristics of esophageal squamous papillomas (ESPs) in the Japanese population, we investigated 38 ESPs of 35 Japanese patients from a file with 17,387 upper gastrointestinal endoscopies in our university hospital. ESPs accounted for 0.20% of the total number of endoscopies and comprised 21 females and 14 males with an average age of 59.2 years. More than half of the ESPs (52.6%) were located in the middle esophagus. The ratio of human papilloma virus (HPV) positive ESPs was 10.5% and all were located in the middle esophagus of female patients only. HPV-positive ESP cases were younger (46.8 years) than HPV-negative cases (60.8 years). Based on comparison with the reports from western countries, we attribute the low prevalence in the lower esophagus to the relatively fewer occurrences of severe reflux esophagitis (RE) due to chronic gastritis with low gastric acid secretion among Japanese patients.

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