GenABEL: an R Library for Genome-wide Association Analysis

Overview

Journal Bioinformatics

Publisher Oxford University Press

Specialty Biology

Date 2007 Mar 27

PMID 17384015

Citations 1015

Authors

Yurii S Aulchenko

Stephan Ripke

Aaron Isaacs

Cornelia M Van Duijn

Affiliations

Soon will be listed here.

Abstract

Unlabelled: Here we describe an R library for genome-wide association (GWA) analysis. It implements effective storage and handling of GWA data, fast procedures for genetic data quality control, testing of association of single nucleotide polymorphisms with binary or quantitative traits, visualization of results and also provides easy interfaces to standard statistical and graphical procedures implemented in base R and special R libraries for genetic analysis. We evaluated GenABEL using one simulated and two real data sets. We conclude that GenABEL enables the analysis of GWA data on desktop computers.

Availability: http://cran.r-project.org.

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