Temporal Frequency of Subthreshold Oscillations Scales with Entorhinal Grid Cell Field Spacing

Overview

Journal Science

Specialty Science

Date 2007 Mar 24

PMID 17379810

Citations 203

Authors

Lisa M Giocomo

Eric A Zilli

Erik Fransen

Michael E Hasselmo

Affiliations

Soon will be listed here.

Abstract

Grid cells in layer II of rat entorhinal cortex fire to spatial locations in a repeating hexagonal grid, with smaller spacing between grid fields for neurons in more dorsal anatomical locations. Data from in vitro whole-cell patch recordings showed differences in frequency of subthreshold membrane potential oscillations in entorhinal neurons that correspond to different positions along the dorsal-to-ventral axis, supporting a model of physiological mechanisms for grid cell responses.

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