Effects of Oregano, Carvacrol and Thymol on Staphylococcus Aureus and Staphylococcus Epidermidis Biofilms

Overview

Journal J Med Microbiol

Specialty Microbiology

Date 2007 Mar 22

PMID 17374894

Citations 144

Authors

Antonia Nostro

Andrea Sudano Roccaro

Giuseppe Bisignano

Andreana Marino

Maria A Cannatelli

Francesco C Pizzimenti

Pier Luigi Cioni

Francesca Procopio

Anna Rita Blanco

Affiliations

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Abstract

The aim of this study was to evaluate the effect of oregano essential oil, carvacrol and thymol on biofilm-grown Staphylococcus aureus and Staphylococcus epidermidis strains, as well as the effects of the oils on biofilm formation. For most of the S. aureus (n=6) and S. epidermidis (n=6) strains tested, the biofilm inhibitory concentration (0.125-0.500 %, v/v, for oregano, and 0.031-0.125 %, v/v, for carvacrol and thymol) and biofilm eradication concentration (0.25-1.0 %, v/v, for oregano and 0.125-0.500 %, v/v, for carvacrol and thymol) values were twofold or fourfold greater than the concentration required to inhibit planktonic growth. Subinhibitory concentrations of the oils attenuated biofilm formation of S. aureus and S. epidermidis strains on polystyrene microtitre plates.

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