» Articles » PMID: 17362197

The Machines That Divide and Fuse Mitochondria

Overview
Publisher Annual Reviews
Specialty Biochemistry
Date 2007 Mar 17
PMID 17362197
Citations 406
Authors
Affiliations
Soon will be listed here.
Abstract

Mitochondria are derived from eubacteria; however, in most eukaryotes, novel mechanisms for the propagation of this organelle and its genome have evolved. This review focuses on what is currently known about the novel molecular machines that divide and fuse mitochondria.

Citing Articles

Zephycandidine A and Synthetic Analogues-Synthesis and Evaluation of Biological Activity.

Klassmuller T, Lengauer F, Blenninger J, Geisslinger F, Bartel K, Bracher F Molecules. 2025; 30(3).

PMID: 39942855 PMC: 11820727. DOI: 10.3390/molecules30030752.


Significantly reduced, but balanced, rates of mitochondrial fission and fusion are sufficient to maintain the integrity of yeast mitochondrial DNA.

Wisniewski B, Casler J, Lackner L Mol Biol Cell. 2024; 35(12):br25.

PMID: 39535883 PMC: 11656474. DOI: 10.1091/mbc.E24-07-0306.


20 (S)-Protopanaxadiol Alleviates DRP1-Mediated Mitochondrial Dysfunction in a Depressive Model In Vitro and In Vivo via the SIRT1/PGC-1α Signaling Pathway.

Guo P, Wang Z, Sun L, He Z, Li J, Geng J Molecules. 2024; 29(21).

PMID: 39519726 PMC: 11547436. DOI: 10.3390/molecules29215085.


Mitochondrial Dynamics in Non-Small Cell Lung Cancer.

Dutkowska A, Domanska-Senderowska D, Czarnecka-Chrebelska K, Pikus E, Zielinska A, Biskup L Cancers (Basel). 2024; 16(16).

PMID: 39199596 PMC: 11352408. DOI: 10.3390/cancers16162823.


With age comes resilience: how mitochondrial modulation drives age-associated fluconazole tolerance in .

Yoo K, Bhattacharya S, Oliveira N, Pereira De Sa N, Matos G, Del Poeta M mBio. 2024; 15(9):e0184724.

PMID: 39136442 PMC: 11389405. DOI: 10.1128/mbio.01847-24.