Resistance of Trichostrongyles to Benzimidazoles in Italy: a First Report in a Goat Farm with Multiple and Repeated Introductions

Overview

Journal Parasitol Res

Specialty Parasitology

Date 2007 Mar 16

PMID 17356891

Citations 16

Authors

G Cringoli

V Veneziano

L Rinaldi

C Sauve

R Rubino

V Fedele

J Cabaret

Affiliations

Soon will be listed here.

Abstract

Anthelmintic resistance is widely distributed in small ruminants throughout the world. The extension of resistance seems lower in southern European countries and has not been reported previously in Italy. In the present study, resistance to benzimidazoles, levamisole and ivermectin was evaluated in a multi-breed goat farm of southern Italy. The farm had a history of repeated goat introductions from other flocks and a moderate regimen of anthelmintic treatments using alternatively the three above-mentioned drugs. Resistance of gastrointestinal strongyles was studied on the basis of faecal egg counts, egg hatch assay and necropsies. Resistance to anthelmintics was evidenced for benzimidazoles only, and Trichostrongylus colubriformis was the only resistant strongyle species. Single drug and single species resistance suggest that resistance is on its beginning and that measures for reducing the spread of resistance are of interest and should be promoted.

Citing Articles

Effect of pomegranate () anthelmintic treatment on milk production in dairy sheep naturally infected with gastrointestinal nematodes.

Castagna F, Bava R, Palma E, Morittu V, Spina A, Ceniti C Front Vet Sci. 2024; 11:1347151.

PMID: 38384955 PMC: 10879392. DOI: 10.3389/fvets.2024.1347151.

Control of gastrointestinal helminths in small ruminants to prevent anthelmintic resistance: the Italian experience.

Maurizio A, Perrucci S, Tamponi C, Scala A, Cassini R, Rinaldi L Parasitology. 2023; 150(12):1105-1118.

PMID: 37039466 PMC: 10801368. DOI: 10.1017/S0031182023000343.

First Report of Anthelmintic Resistance in Gastrointestinal Nematodes in Goats in Romania.

Potarniche A, Mickiewicz M, Olah D, Cerbu C, Spinu M, Hari A Animals (Basel). 2021; 11(10).

PMID: 34679782 PMC: 8532838. DOI: 10.3390/ani11102761.

Preliminary Assessment of Body Condition Score as a Possible Marker for the Targeted Selective Treatment of Dairy Sheep Against Gastrointestinal Nematodes.

Tamponi C, Dessi G, Varcasia A, Knoll S, Meloni L, Scala A Acta Parasitol. 2021; 67(1):362-368.

PMID: 34613573 PMC: 8938367. DOI: 10.1007/s11686-021-00470-9.

Multiple Anthelmintic Resistance at a Goat Farm in Slovakia.

Babjak M, Konigova A, Varady M Helminthologia. 2021; 58(2):173-178.

PMID: 34248377 PMC: 8256461. DOI: 10.2478/helm-2021-0014.

References

Cringoli G . FLOTAC, a novel apparatus for a multivalent faecal egg count technique. Parassitologia. 2006; 48(3):381-4. View

Van Wyk J, Cabaret J, Michael L . Morphological identification of nematode larvae of small ruminants and cattle simplified. Vet Parasitol. 2004; 119(4):277-306. DOI: 10.1016/j.vetpar.2003.11.012. View

Gaba S, Chadoeuf J, Monestiez P, Sauve C, Cortet J, Cabaret J . Estimation of abomasum strongyle nematode infections in sheep at necropsy: tentative proposals for a simplified technique. Vet Parasitol. 2006; 140(1-2):105-13. DOI: 10.1016/j.vetpar.2006.03.021. View

Cabaret J, Berrag B . Faecal egg count reduction test for assessing anthelmintic efficacy: average versus individually based estimations. Vet Parasitol. 2004; 121(1-2):105-13. DOI: 10.1016/j.vetpar.2004.01.020. View

Kochapakdee S, Pandey V, Pralomkarn W, Choldumrongkul S, Ngampongsai W, Lawpetchara A . Anthelmintic resistance in goats in southern Thailand. Vet Rec. 1995; 137(5):124-5. DOI: 10.1136/vr.137.5.124. View

Chartier C, Soubirac F, Pors I, Silvestre A, Hubert J, Couquet C . Prevalence of anthelmintic resistance in gastrointestinal nematodes of dairy goats under extensive management conditions in southwestern France. J Helminthol. 2002; 75(4):325-30. DOI: 10.1017/s0022149x01000506. View

Papadopoulos E, Himonas C, Coles G . Drought and flock isolation may enhance the development of anthelmintic resistance in nematodes. Vet Parasitol. 2001; 97(4):253-9. DOI: 10.1016/s0304-4017(01)00435-6. View

Mejia M, Fernandez Igartua B, Schmidt E, Cabaret J . Multispecies and multiple anthelmintic resistance on cattle nematodes in a farm in Argentina: the beginning of high resistance?. Vet Res. 2003; 34(4):461-7. DOI: 10.1051/vetres:2003018. View

Alvarez-Sanchez M, Perez-Garcia J, Cruz-Rojo M, Rojo-Vazquez F . Anthelmintic resistance in trichostrongylid nematodes of sheep farms in Northwest Spain. Parasitol Res. 2006; 99(1):78-83. DOI: 10.1007/s00436-006-0130-2. View

10.

Faizal A, Rajapaksha W, Rajapakse R . Benefit of the control of gastrointestinal nematode infection in goats in the dry zone of Sri Lanka. J Vet Med B Infect Dis Vet Public Health. 2002; 49(3):115-9. DOI: 10.1046/j.1439-0450.2002.00511.x. View

11.

Dash K, Hall E, Barger I . The role of arithmetic and geometric mean worm egg counts in faecal egg count reduction tests and in monitoring strategic drenching programs in sheep. Aust Vet J. 1988; 65(2):66-8. DOI: 10.1111/j.1751-0813.1988.tb07359.x. View

12.

Chartier C, Etter E, Hoste H, Pors I, Mallereau M, Broqua C . Effects of the initial level of milk production and of the dietary protein intake on the course of natural nematode infection in dairy goats. Vet Parasitol. 2000; 92(1):1-13. DOI: 10.1016/s0304-4017(00)00268-5. View

13.

Coles G, Bauer C, Borgsteede F, Geerts S, Klei T, Taylor M . World Association for the Advancement of Veterinary Parasitology (W.A.A.V.P.) methods for the detection of anthelmintic resistance in nematodes of veterinary importance. Vet Parasitol. 1992; 44(1-2):35-44. DOI: 10.1016/0304-4017(92)90141-u. View

14.

Coles G, Jackson F, Pomroy W, Prichard R, von Samson-Himmelstjerna G, Silvestre A . The detection of anthelmintic resistance in nematodes of veterinary importance. Vet Parasitol. 2006; 136(3-4):167-85. DOI: 10.1016/j.vetpar.2005.11.019. View

15.

Bentounsi B, Trad R, Gaous N, Kohil K, Cabaret J . Gastrointestinal nematode resistance to benzimidazoles on a sheep farm in Algeria. Vet Rec. 2006; 158(18):634-5. DOI: 10.1136/vr.158.18.634. View

16.

Jackson F, Jackson E, Little S, Coop R, Russel A . Prevalence of anthelmintic-resistant nematodes in fibre-producing goats in Scotland. Vet Rec. 1992; 131(13):282-5. DOI: 10.1136/vr.131.13.282. View

17.

Silvestre A, Leignel V, Berrag B, Gasnier N, Humbert J, Chartiere C . Sheep and goat nematode resistance to anthelmintics: pro and cons among breeding management factors. Vet Res. 2002; 33(5):465-80. DOI: 10.1051/vetres:2002033. View

18.

Martinez A, Meana A, Rojo-Vazquez F, Osoro K, Ortega-Mora L . Anthelmintic resistance in nematode parasites from goats in Spain. Vet Parasitol. 1998; 73(1-2):83-8. DOI: 10.1016/s0304-4017(97)00043-5. View