Leishmanicidal Activity of Pentalinon Andrieuxii

Overview

Journal Fitoterapia

Publisher Elsevier

Specialties Pharmacology
Rehabilitation Medicine

Date 2007 Mar 16

PMID 17355903

Citations 8

Authors

Claudio M Lezama-Davila

Angelica P Isaac-Marquez

Pedro Zamora-Crescencio

Mirna del R Uc-Encalada

Sonia Y Justiniano-Apolinar

Leticia del Angel-Robles

Abhay Satoskar

Laritza Hernandez-Rivero

Affiliations

Soon will be listed here.

Abstract

Extracts of the root of Pentalinon andrieuxii, vernacular name of "contrahierva" (solen ak' in Mayan language, were investigated for their lethal effect on the protozoa Leishmania mexicana. The hexanes extract was highly effective to delay and eventually stop parasite survival.

Citing Articles

Pentalinonsterol, a Phytosterol from Pentalinon andrieuxii, is Immunomodulatory through Phospholipase A in Macrophages toward its Antileishmanial Action.

Varikuti S, Shelton A, Kotha S, Gurney T, Gupta G, Hund T Cell Biochem Biophys. 2021; 80(1):45-61.

PMID: 34387841 DOI: 10.1007/s12013-021-01030-8.

The Potential of Traditional Knowledge to Develop Effective Medicines for the Treatment of Leishmaniasis.

Passero L, Brunelli E, Sauini T, Amorim Pavani T, Jesus J, Rodrigues E Front Pharmacol. 2021; 12:690432.

PMID: 34220515 PMC: 8248671. DOI: 10.3389/fphar.2021.690432.

Pentalinonsterol, a Constituent of Pentalinon andrieuxii, Possesses Potent Immunomodulatory Activity and Primes T Cell Immune Responses.

Oghumu S, Varikuti S, Saljoughian N, Terrazas C, Huntsman A, Parinandi N J Nat Prod. 2017; 80(9):2515-2523.

PMID: 28876059 PMC: 5731641. DOI: 10.1021/acs.jnatprod.7b00445.

A Novel Sterol Isolated from a Plant Used by Mayan Traditional Healers Is Effective in Treatment of Visceral Leishmaniasis Caused by Leishmania donovani.

Gupta G, Peine K, Abdelhamid D, Snider H, Shelton A, Rao L ACS Infect Dis. 2016; 1(10):497-506.

PMID: 27623316 PMC: 5730984. DOI: 10.1021/acsinfecdis.5b00081.

A New Antileishmanial Preparation of Combined Solamargine and Solasonine Heals Cutaneous Leishmaniasis through Different Immunochemical Pathways.

Lezama-Davila C, McChesney J, Bastos J, Miranda M, Tiossi R, da Costa J Antimicrob Agents Chemother. 2016; 60(5):2732-8.

PMID: 26883711 PMC: 4862480. DOI: 10.1128/AAC.02804-15.