[Analysis of Coumarins in Fructus Cnidii by HPLC-ESI-MS]

Overview

Journal Zhong Yao Cai

Specialty Rehabilitation Medicine

Date 2007 Mar 1

PMID 17326403

Citations 2

Authors

Ying-Qiao Jiang

Affiliations

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Abstract

Objective: To analyze coumarins in Fructus Cnidii by HPLC-ESI-MS.

Methods: Coumarins in Fructus Cnidii were subjected to HPLC, using Shim-pack CLC-ODS column, methanol-water (70:30) as mobile phase, and 254 nm as DAD wavelength. A quadrupole mass spectrometer was applied to verify the LC elute, operated in the positive ion mode.

Results: Three coumarins were determined and the possible structures of seven coumarins were deduced based on the chromatography and MS data.

Conclusion: The application of this method could be available for the rapid identification of constituents from traditional Chinese medicines.

Citing Articles

Synergic Anti-Pruritus Mechanisms of Action for the Radix Sophorae Flavescentis and Fructus Cnidii Herbal Pair.

Zhong J, Liu Z, Zhou X, Xu J Molecules. 2017; 22(9).

PMID: 28869563 PMC: 6151778. DOI: 10.3390/molecules22091465.

Electrochemical reduction of coumarins at a film-modified electrode and determination of their levels in essential oils and traditional Chinese herbal medicines.

Wang L, Liu H Molecules. 2009; 14(9):3538-50.

PMID: 19783942 PMC: 6254838. DOI: 10.3390/molecules14093538.