Comparison of High Order Aberration After Conventional and Customized Ablation in Myopic LASIK in Different Eyes of the Same Patient

Overview

Journal J Zhejiang Univ Sci B

Specialties Biology
General Medicine

Date 2007 Feb 27

PMID 17323429

Citations 6

Authors

Chi-Xin Du

Ye Shen

Yang Wang

Affiliations

Soon will be listed here.

Abstract

Purpose: To verify whether there exists any difference in higher order aberrations after undergoing myopic LASIK (laser in situ keratomileusis) with conventional ablation and customized ablation in different eyes of the same patient.

Methods: This was a prospective randomized study of 54 myopic eyes (27 patients) that underwent LASIK using the Nidek EC-5000 excimer laser system (Nidek, Gamagori, Japan). Topography-guided customized aspheric treatment zone (CATz) was used in the first eye of the patient (study group) and the other eye of the same patient was operated on with conventional ablation (control group). Higher order aberrations [root-mean-square (RMS) in the 5-mm zone] of both groups were observed with the Nidek OPD-Scan aberrometer before and 3 months after LASIK. Preoperative mean refractive error was similar between two eyes of the same patient (t=-0.577, P>0.05).

Results: Preoperatively, higher order aberrations (RMS in the 5-mm zone) in the CATz ablation and conventional groups were (0.3600+/-0.0341) microm and (0.2680+/-0.1421) microm, respectively. This difference was not statistically significant (t=1.292, P>0.05). Three months after LASIK, higher order aberrations (RMS in 5-mm zone) in the CATz ablation and conventional groups were (0.3627+/-0.1510) microm and (0.3991+/-0.1582) microm, respectively. No statistically significant difference was noted between pre- and postoperative higher order aberrations in the CATz group (t=-0.047, P>0.05). However, a statistically significant increase in higher order aberrations was observed after conventional ablation (t=-5.261, P<0.05). A statistically significant difference was noted in the increase of higher order aberrations after LASIK between groups (t=-2.050, P=0.045).

Conclusion: LASIK with conventional ablation and topography-guided CATz ablation resulted in the same BSCVA (best spectacle-corrected visual acuity) 3 month after LASIK. Higher order aberrations were increased, but the increase of higher order aberrations after customized ablation treatment was less than that after conventional ablation.

Citing Articles

Clinical outcomes of topography-guided versus wavefront-optimized LASIK for correction of myopia and compound myopic astigmatism.

Rani D, Khokhar S, Rathod A, Nathiya V, Pujari A, Gupta T Indian J Ophthalmol. 2024; 72(11):1598-1604.

PMID: 38767561 PMC: 11668192. DOI: 10.4103/IJO.IJO_2012_23.

Visual differences in topography-guided versus wavefront-optimized LASIK in the treatment of myopia: a Meta-analysis.

Hu P, Li L, Wu X, Li Y, Li K Int J Ophthalmol. 2021; 14(10):1602-1609.

PMID: 34667739 PMC: 8482009. DOI: 10.18240/ijo.2021.10.19.

Wavefront excimer laser refractive surgery for adults with refractive errors.

Li S, Kang M, Wang N, Abariga S Cochrane Database Syst Rev. 2020; 12:CD012687.

PMID: 33336797 PMC: 8094180. DOI: 10.1002/14651858.CD012687.pub2.

Visual Outcomes and Higher Order Aberrations Following LASIK on Eyes with Low Myopia and Astigmatism.

Agarwal S, Thornell E, Hodge C, Sutton G, Hughes P Open Ophthalmol J. 2018; 12:84-93.

PMID: 29997707 PMC: 5997857. DOI: 10.2174/1874364101812010084.

Photorefractive keratectomy for myopia and myopic astigmatism correction using the WaveLight Allegretto Wave Eye-Q excimer laser system.

Costa E, Franqueira N, Rosa A, Tavares C, Quadrado M, Lobo C Int Ophthalmol. 2013; 34(3):477-84.

PMID: 23872862 DOI: 10.1007/s10792-013-9833-4.

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