Perioperative Auricular Electroacupuncture Has No Effect on Pain and Analgesic Consumption After Third Molar Tooth Extraction
Overview
Authors
Affiliations
Background: Auricular acupuncture (AA) has been shown to alleviate acute and chronic pain. We investigated the effects of auricular electroacupuncture (AE) on pain and analgesic drug consumption in the first 48 h after unilateral mandibular third molar tooth extraction under local anesthesia in a prospective, randomized, double-blind, placebo-controlled study in 149 patients.
Methods: Patients received either AA with electrical stimulation (AE, n = 76) or without (AA, n = 37) electrical stimulation at an alternating frequency of 2/100 Hz or a sham AE with metal plates instead of needles and no electrical stimulation, no-needle (NN, n = 36) at the AA points 1 (tooth), 55 (Shen men) and 84 (mouth) during the entire study period. Regularly rated pain intensity (five-point verbal rating scale), consumption of acetaminophen 500 mg tablets and additional rescue medication with mefenamic acid 500 mg were assessed.
Results: The median fraction of time when pain was rated as moderate or worse (upper and lower quartile): AE: 33% (12%, 64%), AA: 22% (6%, 56%), NN: 30% (7%, 53%) did not differ significantly among the treatment groups. There were no significant differences in mean number of acetaminophen 500 mg tablets (range): AE: 5.2 (0-12), AA: 4.6 (0-11), NN: 5.4 (0-10) or percentage of patients requiring additional mefenamic acid: AE: 19%, AA: 18%, NN: 19%.
Conclusion: We conclude that neither AE nor AA alone reduce either pain intensity or analgesic consumption in a molar tooth extraction model of acute pain.
Sarkar T, Pandya D, Sharma M, Kulavi S, Dausage P, Banerjee A J Pharm Bioallied Sci. 2025; 16(Suppl 4):S3628-S3630.
PMID: 39926999 PMC: 11805018. DOI: 10.4103/jpbs.jpbs_1108_24.
Zhou Y, Bao Q, Yang C, Li S, Yin Z, Xiong J J Pain Res. 2025; 18:441-454.
PMID: 39882182 PMC: 11776400. DOI: 10.2147/JPR.S488525.
Choi S, Baek I, Lee K, Kim S Korean J Physiol Pharmacol. 2024; 29(1):109-116.
PMID: 39482237 PMC: 11694001. DOI: 10.4196/kjpp.24.266.
Duff I, Likar R, Perruchoud C, Kampusch S, Kostenberger M, Sator S Pain Ther. 2024; 13(6):1407-1427.
PMID: 39382792 PMC: 11543973. DOI: 10.1007/s40122-024-00657-8.
Ilfeld B, Finneran 4th J, Alexander B, Abramson W, Sztain J, Ball S Reg Anesth Pain Med. 2024; 50(1):26-35.
PMID: 38388019 PMC: 11877037. DOI: 10.1136/rapm-2023-105028.