Tissue Microarrays Characterise the Clinical Significance of a VEGF-A Protein Expression Signature in Gastrointestinal Stromal Tumours

Overview

Journal Br J Cancer

Specialty Oncology

Date 2007 Feb 15

PMID 17299397

Citations 11

Authors

M Salto-Tellez

M E Nga

H C Han

A S-C Wong

C K Lee

D Anuar

S S Ng

M Ho

A Wee

Y H Chan

R Soong

Affiliations

Soon will be listed here.

Abstract

A tissue microarray analysis of 22 proteins in gastrointestinal stromal tumours (GIST), followed by an unsupervised, hierarchical monothetic cluster statistical analysis of the results, allowed us to detect a vascular endothelial growth factor (VEGF) protein overexpression signature discriminator of prognosis in GIST, and discover novel VEGF-A DNA variants that may have functional significance.

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