[Associated Diseases and Differential Diagnostic Considerations in Childhood Atopic Eczema]

Overview

Journal Hautarzt

Specialty Dermatology

Date 2007 Feb 3

PMID 17268788

Citations 3

Authors

C Jenneck

R Foelster-Holst

T Hagemann

N Novak

Affiliations

Soon will be listed here.

Abstract

Atopic eczema (AE) is a chronic inflammatory skin disease which affects 10 to 20% of children and 1 to 3% of adults. AE is usually diagnosed based on standard criteria such as those of Hanifin and Rajka, whereby the age-related variation must be considered. There are numerous other diseases which go along with AE or show a very similar clinical picture and represent important differential diagnostic considerations including parasitic diseases, immunodeficiency, nutritional diseases, certain neoplastic disorders and various corneal abnormalities. Additionally, it is important to consider diseases which can occur in association with AE, such as keratosis pilaris, alopecia areata or sweat disturbances.

Citing Articles

[Information needs of patients with atopic eczema-a qualitative study].

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[Neurodermatitis : Atopy of the skin].

Folster-Holst R Ophthalmologe. 2017; 114(6):498-503.

PMID: 28447153 DOI: 10.1007/s00347-017-0495-x.

S2k guideline on diagnosis and treatment of atopic dermatitis - short version.

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PMID: 27239428 PMC: 4861742. DOI: 10.1007/s40629-016-0110-8.

References

Chavanas S, Garner C, Bodemer C, Ali M, Teillac D, Wilkinson J . Localization of the Netherton syndrome gene to chromosome 5q32, by linkage analysis and homozygosity mapping. Am J Hum Genet. 2000; 66(3):914-21. PMC: 1288172. DOI: 10.1086/302824. View

Motil K, Fete T, Fraley J, Schultz R, Foy T, Ochs U . Growth characteristics of children with ectodermal dysplasia syndromes. Pediatrics. 2005; 116(2):e229-34. DOI: 10.1542/peds.2004-2830. View

Giliani S, Bonfim C, de Saint Basile G, Lanzi G, Brousse N, Koliski A . Omenn syndrome in an infant with IL7RA gene mutation. J Pediatr. 2006; 148(2):272-4. DOI: 10.1016/j.jpeds.2005.10.004. View

Folster-Holst R, Weichenthal M, Steinsland K, Polzhofer G, Christophers E . Eczema infantum and its prognosis. Acta Derm Venereol. 2004; 84(5):410-12. View

Rust R, Kluiver J, Visser L, Harms G, Blokzijl T, Kamps W . Gene expression analysis of dendritic/Langerhans cells and Langerhans cell histiocytosis. J Pathol. 2006; 209(4):474-83. DOI: 10.1002/path.2003. View

Clarke A, Sarfarazi M, Thomas N, Roberts K, Harper P . X-linked hypohidrotic ectodermal dysplasia: DNA probe linkage analysis and gene localization. Hum Genet. 1987; 75(4):378-80. DOI: 10.1007/BF00284112. View

Safavi K, Muller S, Suman V, Moshell A, Melton 3rd L . Incidence of alopecia areata in Olmsted County, Minnesota, 1975 through 1989. Mayo Clin Proc. 1995; 70(7):628-33. DOI: 10.4065/70.7.628. View

Sullivan K . The clinical, immunological, and molecular spectrum of chromosome 22q11.2 deletion syndrome and DiGeorge syndrome. Curr Opin Allergy Clin Immunol. 2005; 4(6):505-12. DOI: 10.1097/00130832-200412000-00006. View

Kere J, Srivastava A, Montonen O, Zonana J, Thomas N, Ferguson B . X-linked anhidrotic (hypohidrotic) ectodermal dysplasia is caused by mutation in a novel transmembrane protein. Nat Genet. 1996; 13(4):409-16. DOI: 10.1038/ng0895-409. View

10.

Finocchi A, Di Cesare S, Romiti M, Capponi C, Rossi P, Carsetti R . Humoral immune responses and CD27+ B cells in children with DiGeorge syndrome (22q11.2 deletion syndrome). Pediatr Allergy Immunol. 2006; 17(5):382-8. DOI: 10.1111/j.1399-3038.2006.00409.x. View

11.

Mevorah B, Marazzi A, Frenk E . The prevalence of accentuated palmoplantar markings and keratosis pilaris in atopic dermatitis, autosomal dominant ichthyosis and control dermatological patients. Br J Dermatol. 1985; 112(6):679-85. DOI: 10.1111/j.1365-2133.1985.tb02336.x. View

12.

Cole H, Weremowicz S, Morton C, Wolf B . Localization of serum biotinidase (BTD) to human chromosome 3 in band p25. Genomics. 1994; 22(3):662-3. DOI: 10.1006/geno.1994.1449. View

13.

Smith F, Irvine A, Terron-Kwiatkowski A, Sandilands A, Campbell L, Zhao Y . Loss-of-function mutations in the gene encoding filaggrin cause ichthyosis vulgaris. Nat Genet. 2006; 38(3):337-42. DOI: 10.1038/ng1743. View

14.

Santagata S, Villa A, Sobacchi C, Cortes P, Vezzoni P . The genetic and biochemical basis of Omenn syndrome. Immunol Rev. 2001; 178:64-74. DOI: 10.1034/j.1600-065x.2000.17818.x. View

15.

Charuwichitratana S, Wattanakrai P, Tanrattanakorn S . Randomized double-blind placebo-controlled trial in the treatment of alopecia areata with 0.25% desoximetasone cream. Arch Dermatol. 2000; 136(10):1276-7. DOI: 10.1001/archderm.136.10.1276. View

16.

Krol A, Krafchik B . The differential diagnosis of atopic dermatitis in childhood. Dermatol Ther. 2006; 19(2):73-82. DOI: 10.1111/j.1529-8019.2006.00058.x. View

17.

HYMES J, Stanley C, Wolf B . Mutations in BTD causing biotinidase deficiency. Hum Mutat. 2001; 18(5):375-81. DOI: 10.1002/humu.1208. View

18.

Lehnert T, Kury S, Burk G, Hoepffner W, Schuster V . [Acrodermatitis enteropathica (AE) is caused by mutations in the zinc transporter gene SLC39A4]. Klin Padiatr. 2006; 218(4):221-3. DOI: 10.1055/s-2005-836465. View

19.

Tay Y, Khoo B, Goh C . The epidemiology of atopic dermatitis at a tertiary referral skin center in Singapore. Asian Pac J Allergy Immunol. 2000; 17(3):137-41. View

20.

Kury S, Dreno B, Bezieau S, Giraudet S, Kharfi M, Kamoun R . Identification of SLC39A4, a gene involved in acrodermatitis enteropathica. Nat Genet. 2002; 31(3):239-40. DOI: 10.1038/ng913. View