MiRNAs in the Biology of Cancers and Viral Infections
Overview
Affiliations
MicroRNAs (miRNAs) are non-coding small RNAs that play important roles in a variety of biological pathways including cellular proliferation and apoptosis. Recent studies have linked the expression of selected miRNAs to carcinogenesis and viral pathogenesis. Here, we will discuss examples of roles served by cellular miRNAs and virus-encoded miRNAs in the development of cancers and viral diseases.
Zhu S, Xu H, Chen R, Shen Q, Yang D, Peng H J Cell Mol Med. 2023; 27(6):788-802.
PMID: 36811277 PMC: 10002968. DOI: 10.1111/jcmm.17612.
Small molecule alteration of RNA sequence in cells and animals.
Guan L, Luo Y, Ja W, Disney M Bioorg Med Chem Lett. 2017; 28(16):2794-2796.
PMID: 29079470 PMC: 5906209. DOI: 10.1016/j.bmcl.2017.10.034.
Prinsloo A, Pool R, van Niekerk C Mol Clin Oncol. 2017; 7(3):386-390.
PMID: 28781815 PMC: 5530321. DOI: 10.3892/mco.2017.1319.
MiR-10a* up-regulates coxsackievirus B3 biosynthesis by targeting the 3D-coding sequence.
Tong L, Lin L, Wu S, Guo Z, Wang T, Qin Y Nucleic Acids Res. 2013; 41(6):3760-71.
PMID: 23389951 PMC: 3616696. DOI: 10.1093/nar/gkt058.
A proteomic study of TAR-RNA binding protein (TRBP)-associated factors.
Chi Y, Semmes O, Jeang K Cell Biosci. 2011; 1(1):9.
PMID: 21711701 PMC: 3125213. DOI: 10.1186/2045-3701-1-9.