Management of Skull Based Meningiomas in the Elderly Patient
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Background: The demographic evolution of Western society together with availability of modern imaging techniques leads to an increasing diagnosis of meningioma patients over 70 years of age. This raises the question of appropriate management of this histologically benign tumour in a geriatric population.
Design: Forty-three patients aged over 70 years were analyzed and matched in a retrospective study with a younger group of 89 patients according to tumour size, histology, symptoms, recurrence and presence of neurofibromatosis II.
Results: Changes in postoperative Karnofsky scores were not statistically different between the two age groups. Neurological outcome was worse among the younger group (12% vs. 7% deterioration). Regarding surgical complications we noted only a statistically significant higher infection rate in the geriatric age group. There was no peri-operative mortality.
Conclusions: Age alone is not a criterion to deny a priori skull base surgery, since well selected geriatric patients may benefit from a meningioma operation that may enhance future quality of life.
Ius T, Raffa G, Aiudi D, Panciani P, Pepa G, Pessina F Neurosurg Rev. 2024; 47(1):373.
PMID: 39083092 PMC: 11291526. DOI: 10.1007/s10143-024-02524-8.
Chen Z, Lin T, Liu D, Zeng Y, Zhang X, Deng B Neuropsychiatr Dis Treat. 2023; 19:2331-2340.
PMID: 37928167 PMC: 10624188. DOI: 10.2147/NDT.S428341.
Przybylowski C, Shaftel K, Hendricks B, Chapple K, Stevens S, Porter R J Neurol Surg B Skull Base. 2022; 83(4):411-417.
PMID: 35903656 PMC: 9324320. DOI: 10.1055/s-0041-1736408.
Case Series of Skull Base Meningioma Resection in the Octogenarian Population.
Kusyk D, Mao G, Dabecco R, Yu A J Neurol Surg B Skull Base. 2022; 83(Suppl 2):e69-e74.
PMID: 35832965 PMC: 9272315. DOI: 10.1055/s-0040-1722711.
Armocida D, Arcidiacono U, Palmieri M, Pesce A, Cofano F, Picotti V Diagnostics (Basel). 2022; 12(2).
PMID: 35204442 PMC: 8871449. DOI: 10.3390/diagnostics12020351.