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Management of Skull Based Meningiomas in the Elderly Patient

Overview
Journal J Clin Neurosci
Specialty Neurology
Date 2007 Jan 30
PMID 17258130
Citations 18
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Abstract

Background: The demographic evolution of Western society together with availability of modern imaging techniques leads to an increasing diagnosis of meningioma patients over 70 years of age. This raises the question of appropriate management of this histologically benign tumour in a geriatric population.

Design: Forty-three patients aged over 70 years were analyzed and matched in a retrospective study with a younger group of 89 patients according to tumour size, histology, symptoms, recurrence and presence of neurofibromatosis II.

Results: Changes in postoperative Karnofsky scores were not statistically different between the two age groups. Neurological outcome was worse among the younger group (12% vs. 7% deterioration). Regarding surgical complications we noted only a statistically significant higher infection rate in the geriatric age group. There was no peri-operative mortality.

Conclusions: Age alone is not a criterion to deny a priori skull base surgery, since well selected geriatric patients may benefit from a meningioma operation that may enhance future quality of life.

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From data to practice: brain meningioma treatment in elderly patients - a survey of the Italian Society of Neurosurgery (SINch®) and systematic review and meta-analysis.

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Comparison of Short-Term Surgery Outcomes and Clinical Characteristics Between Elderly and Non-Elderly Patients with Middle Third Parasagittal and Parafalcine Meningiomas.

Chen Z, Lin T, Liu D, Zeng Y, Zhang X, Deng B Neuropsychiatr Dis Treat. 2023; 19:2331-2340.

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Perioperative Complication Profile of Skull Base Meningioma Resection in Older versus Younger Adult Patients.

Przybylowski C, Shaftel K, Hendricks B, Chapple K, Stevens S, Porter R J Neurol Surg B Skull Base. 2022; 83(4):411-417.

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Case Series of Skull Base Meningioma Resection in the Octogenarian Population.

Kusyk D, Mao G, Dabecco R, Yu A J Neurol Surg B Skull Base. 2022; 83(Suppl 2):e69-e74.

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Intracranial Meningioma in Elderly Patients. Retrospective Multicentric Risk and Surgical Factors Study of Morbidity and Mortality.

Armocida D, Arcidiacono U, Palmieri M, Pesce A, Cofano F, Picotti V Diagnostics (Basel). 2022; 12(2).

PMID: 35204442 PMC: 8871449. DOI: 10.3390/diagnostics12020351.