Complementation and Noncomplementation Among Nonallelic Mutations Altering Development in SCHIZOPHYLLUM COMMUNE
Overview
Affiliations
Mutations resistant to compounds that alter the development of Schizophyllum commune (cyclic adenosine monophosphate, caffeine and imidazole) were selected. These mutations defined four genes, car (cAMP resistance), caf-1 and caf-2 (caffeine resistance) and imr (imidazole resistance). The mutations were found to be noncomplementing in certain pairs when tested against each other and against two previously isolated developmental mutations, B-con and sep (septateless), in fully compatible, forced heterokaryons. The pattern of complementation in fully compatible diploids showed noncomplementation only between allelic mutations, except for one case, imr vs. car.
A central role for Ras1 in morphogenesis of the basidiomycete Schizophyllum commune.
Knabe N, Jung E, Freihorst D, Hennicke F, Horton J, Kothe E Eukaryot Cell. 2013; 12(6):941-52.
PMID: 23606288 PMC: 3675993. DOI: 10.1128/EC.00355-12.
Baron K, McNamara A, Minke P, Burrascano C, Maddock J Genetics. 1998; 148(1):131-7.
PMID: 9475727 PMC: 1459796. DOI: 10.1093/genetics/148.1.131.
Varkey J, Jansma P, Minniti A, Ward S Genetics. 1993; 133(1):79-86.
PMID: 8417991 PMC: 1205300. DOI: 10.1093/genetics/133.1.79.
McKeon J, Slade E, Sinclair D, Cheng N, Couling M, Brock H Mol Gen Genet. 1994; 244(5):474-83.
PMID: 7915818 DOI: 10.1007/BF00583898.
Atkinson K Genetics. 1985; 111(1):1-6.
PMID: 3896927 PMC: 1202591. DOI: 10.1093/genetics/111.1.1.