» Articles » PMID: 17246099

Induction of Mutations by Gamma-Rays in Pregonial Germ Cells of Zebrafish Embryos

Overview
Journal Genetics
Specialty Genetics
Date 1983 Jan 1
PMID 17246099
Citations 48
Authors
Affiliations
Soon will be listed here.
Abstract

Specific locus (gol-1) germ line mutations are induced by gamma-rays with high frequencies (about 10(-5) r( -1)) during cleavage divisions in zebrafish. Mutant clone sizes range from 3 to 50% of the total number of germ cells, with a mean of about 10%, when embryos are exposed between the 16 and 10(3) cell stages. About five pregonial cells are calculated to be present during the cleavage period.

Citing Articles

Embryonic Lethality, Juvenile Growth Variation, and Adult Sterility Correlate With Phylogenetic Distance of Danionin Hybrids.

Trevena R, Veire B, Chamberlain T, Moravec C, Pelegri F Evol Dev. 2024; 27(1):e12495.

PMID: 39639649 PMC: 11621593. DOI: 10.1111/ede.12495.


Knockout, Knockdown, and the Schrödinger Paradox: Genetic Immunity to Phenotypic Recapitulation in Zebrafish.

Arana A, Sanchez L Genes (Basel). 2024; 15(9).

PMID: 39336755 PMC: 11431394. DOI: 10.3390/genes15091164.


Diving deep: zebrafish models in motor neuron degeneration research.

Garg V, Geurten B Front Neurosci. 2024; 18:1424025.

PMID: 38966756 PMC: 11222423. DOI: 10.3389/fnins.2024.1424025.


Direct male development in chromosomally ZZ zebrafish.

Wilson C, Batzel P, Postlethwait J Front Cell Dev Biol. 2024; 12:1362228.

PMID: 38529407 PMC: 10961373. DOI: 10.3389/fcell.2024.1362228.


A maternal-to-zygotic-transition gene block on the zebrafish sex chromosome.

Wilson C, Postlethwait J G3 (Bethesda). 2024; 14(5).

PMID: 38466753 PMC: 11075544. DOI: 10.1093/g3journal/jkae050.


References
1.
SEARLE A . Evidence from mutable genes concerning the origin of the germ line. Basic Life Sci. 1978; 12:209-24. DOI: 10.1007/978-1-4684-3390-6_16. View

2.
Russell L . Definition of functional units in a small chromosomal segment of the mouse and its use in interpreting the nature of radiation-induced mutations. Mutat Res. 1971; 11(1):107-23. DOI: 10.1016/0027-5107(71)90036-4. View

3.
Chakrabarti S, Streisinger G, Singer F, Walker C . Frequency of gamma-Ray Induced Specific Locus and Recessive Lethal Mutations in Mature Germ Cells of the Zebrafish, BRACHYDANIO RERIO. Genetics. 1983; 103(1):109-23. PMC: 1202016. DOI: 10.1093/genetics/103.1.109. View

4.
Streisinger G, Walker C, Dower N, Knauber D, Singer F . Production of clones of homozygous diploid zebra fish (Brachydanio rerio). Nature. 1981; 291(5813):293-6. DOI: 10.1038/291293a0. View

5.
Abrahamson S, Meyer H, Himoe E, Daniel G . Further evidence demonstrating germinal selection in early premeiotic germ cells of Drosophila males. Genetics. 1966; 54(2):687-96. PMC: 1211193. DOI: 10.1093/genetics/54.2.687. View