Evaluation of the in Vitro Activity of Daptomycin Against 19615 Clinical Isolates of Gram-positive Cocci Collected in North American Hospitals (2002-2005)

Overview

Journal Diagn Microbiol Infect Dis

Specialties Infectious Diseases
Microbiology
Pathology

Date 2007 Jan 24

PMID 17240105

Citations 18

Authors

Michael A Pfaller

Helio S Sader

Ronald N Jones

Affiliations

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Abstract

We evaluated the antimicrobial activity of daptomycin against 19,615 clinical strains consecutively collected by numerous centers located across the United States and Canada (2002-2005). Daptomycin was very active against all indicated species (>99% susceptible), with the highest MIC results being 2, 8, 0.5, and 1 microg/mL for staphylococci, enterococci, beta-hemolytic streptococci, and viridans group streptococci, respectively, and no significant loss in potency was observed over the period studied.

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