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Collision of Adenocarcinoma and Gastrointestinal Stromal Tumour (GIST) in the Stomach: Report of a Case

Overview
Journal Int Semin Surg Oncol
Publisher Biomed Central
Specialty Oncology
Date 2007 Jan 16
PMID 17222335
Citations 17
Authors
Iraklis E Katsoulis
Manuela Bossi
Paul I Richman
Jeremy I Livingstone
Affiliations
Soon will be listed here.
Abstract

A 78-year-old woman was diagnosed with a proximal gastric adenocarcinoma and underwent an elective D2 total gastrectomy with splenectomy. Subsequent histopathology revealed the presence of another tumour at the gastric antrum. This was a small benign gastrointestinal stromal tumour (GIST) mixed with gastric adenocarcinoma cells similar to those of the main gastric tumour i.e. a collision tumour. The literature has only few previous reports of this very rare association. It is not known whether this synchronicity is incidental or there is a causative factor inducing the development of tumours of different histotypes in the same organ. Pathologists, oncologists and surgeons should be aware of this interesting condition.

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