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Miniature Near-infrared Dual-axes Confocal Microscope Utilizing a Two-dimensional Microelectromechanical Systems Scanner

Overview
Journal Opt Lett
Specialty Ophthalmology
Date 2007 Jan 12
PMID 17215937
Citations 33
Authors
Jonathan T C Liu
Michael J Mandella
Hyejun Ra
Larry K Wong
Olav Solgaard
Gordon S Kino
Wibool Piyawattanametha
Christopher H Contag
Thomas D Wang
Affiliations
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Abstract

The first, to our knowledge, miniature dual-axes confocal microscope has been developed, with an outer diameter of 10 mm, for subsurface imaging of biological tissues with 5-7 microm resolution. Depth-resolved en face images are obtained at 30 frames per second, with a field of view of 800 x 100 microm, by employing a two-dimensional scanning microelectromechanical systems mirror. Reflectance and fluorescence images are obtained with a laser source at 785 nm, demonstrating the ability to perform real-time optical biopsy.

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