Ex Vivo Simulation of Drug Action: Quantification of Drug-induced MRNA As a Bridge Between Preclinical and Clinical Trials
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L Parrish M, Wright C, Rivers Y, Argilla D, Collins H, Leeson B J Transl Med. 2010; 8:87.
PMID: 20868515 PMC: 2954848. DOI: 10.1186/1479-5876-8-87.
Trastuzumab-induced CCL20 and interleukin-8 mRNA in human whole blood ex vivo.
Hasegawa S, Kato H, Yamaguchi H, Yohda M, Obara K, Izutsu H Invest New Drugs. 2009; 27(6):579-82.
PMID: 19205624 DOI: 10.1007/s10637-009-9223-y.
Mitsuhashi M, Ogura M, Endo K, Obara K, Izutsu H, Targan S Pharm Res. 2008; 25(5):1116-24.
PMID: 18183479 PMC: 2292497. DOI: 10.1007/s11095-007-9510-2.