Bacteroides Fragilis Synthesizes a DNA Invertase Affecting Both a Local and a Distant Region

Overview

Journal J Bacteriol

Publisher American Society for Microbiology

Specialty Microbiology

Date 2006 Dec 26

PMID 17189372

Citations 10

Authors

Hazeline Roche-Hakansson

Maria Chatzidaki-Livanis

Michael J Coyne

Laurie E Comstock

Affiliations

Soon will be listed here.

Abstract

The activity of a fourth conserved tyrosine site-specific recombinase (Tsr) of Bacteroides fragilis was characterized. Its gene, tsr19, is adjacent to mpi, encoding the global DNA invertase regulating capsular polysaccharide biosynthesis. Unlike the other described Tsrs of B. fragilis, Tsr19 brings about inversion of two DNA regions, one local and one located distantly.

Citing Articles

Analysis of a phase-variable restriction modification system of the human gut symbiont Bacteroides fragilis.

Ben-Assa N, Coyne M, Fomenkov A, Livny J, Robins W, Muniesa M Nucleic Acids Res. 2020; 48(19):11040-11053.

PMID: 33045731 PMC: 7641763. DOI: 10.1093/nar/gkaa824.

Site-Specific Recombination - How Simple DNA Inversions Produce Complex Phenotypic Heterogeneity in Bacterial Populations.

Trzilova D, Tamayo R Trends Genet. 2020; 37(1):59-72.

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Identification and Characterization of a Phase-Variable Element That Regulates the Autotransporter UpaE in Uropathogenic Escherichia coli.

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DNA Inversion Regulates Outer Membrane Vesicle Production in Bacteroides fragilis.

Nakayama-Imaohji H, Hirota K, Yamasaki H, Yoneda S, Nariya H, Suzuki M PLoS One. 2016; 11(2):e0148887.

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Efficient electrotransformation of Bacteroides fragilis.

Ichimura M, Nakayama-Imaohji H, Wakimoto S, Morita H, Hayashi T, Kuwahara T Appl Environ Microbiol. 2010; 76(10):3325-32.

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