Primary Neuroendocrine (merkel Cell) Carcinoma of the Anterior Skull Base

Overview

Journal Skull Base Surg

Publisher Thieme

Date 1997 Jan 1

PMID 17171025

Citations 5

Authors

C Matula

K Roessler

M Burian

H Schuster

S Trattnig

J A Hainfellner

H Budka

Affiliations

Soon will be listed here.

Abstract

A case of a primary neuroendocrine (Merkel cell) carcinoma arising in the anterior skull base involving the dura, both frontal lobes, and the paranasal sinuses is presented. The tumor was completely removed by an enlarged bifrontal transbasal approach. The neuropathological, immunohistological, and electron microscopical investigation revealed all characteristics of a Merkel cell carcinoma, normally presenting as a skin carcinoma of the head and neck. The history, treatment, neuropathology, and possible explanation for this rare manifestation are discussed.

Citing Articles

The Evaluation and Treatment of Merkel Cell Carcinoma and Brain Metastasis: A Case Report and Review of the Literature.

Gaburak P, Brown T, Pursel A, Cardenas Contreras L, Chun M Cureus. 2024; 15(12):e51295.

PMID: 38283504 PMC: 10822684. DOI: 10.7759/cureus.51295.

Unusual skull base metastasis from neuroendocrine tumor: a case report.

Lim K, Valle J, Lamarca A J Med Case Rep. 2019; 13(1):273.

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Merkel Cell Carcinoma with Distant Metastasis to the Clivus Causing Symptoms Mimicking Tolosa-Hunt Syndrome: A Case Report and Literature Review.

Ho K, Drew P, Chuquilin M Front Neurol. 2017; 8:409.

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[Primary cutaneous neuroendocrine carcinoma: report of a new case and literature review].

Boukind S, Elatiqi O, Dlimi M, Elamrani D, Benchamkha Y, Ettalbi S Pan Afr Med J. 2015; 20:395.

PMID: 26185585 PMC: 4499317. DOI: 10.11604/pamj.2015.20.395.6149.

Clinical emergence of neurometastatic merkel cell carcinoma: a surgical case series and literature review.

Bailey T, Fung M, Gandour-Edwards R, Ellis W, Schrot R J Neurooncol. 2010; 102(1):147-55.

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