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Mouse Phenome Database (MPD)

Overview
Specialty Biochemistry
Date 2006 Dec 8
PMID 17151079
Citations 55
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Abstract

The Mouse Phenome Database (MPD; http://www.jax.org/phenome) is a repository of phenotypic and genotypic data on commonly used and genetically diverse inbred strains of mice. Strain characteristics data are contributed by members of the scientific community. Electronic access to centralized strain data enables biomedical researchers to choose appropriate strains for many systems-based research applications, including physiological studies, drug and toxicology testing and modeling disease processes. MPD provides a community data repository and a platform for data analysis and in silico hypothesis testing. The laboratory mouse is a premier genetic model for understanding human biology and pathology; MPD facilitates research that uses the mouse to identify and determine the function of genes participating in normal and disease pathways.

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References
1.
Wheeler D, Barrett T, Benson D, Bryant S, Canese K, Chetvernin V . Database resources of the National Center for Biotechnology Information. Nucleic Acids Res. 2005; 34(Database issue):D173-80. PMC: 1347520. DOI: 10.1093/nar/gkj158. View

2.
Birney E, Andrews D, Caccamo M, Chen Y, Clarke L, Coates G . Ensembl 2006. Nucleic Acids Res. 2005; 34(Database issue):D556-61. PMC: 1347495. DOI: 10.1093/nar/gkj133. View

3.
Blake J, Eppig J, Bult C, Kadin J, Richardson J . The Mouse Genome Database (MGD): updates and enhancements. Nucleic Acids Res. 2005; 34(Database issue):D562-7. PMC: 1347448. DOI: 10.1093/nar/gkj085. View

4.
McClurg P, Pletcher M, Wiltshire T, Su A . Comparative analysis of haplotype association mapping algorithms. BMC Bioinformatics. 2006; 7:61. PMC: 1409800. DOI: 10.1186/1471-2105-7-61. View

5.
Fenske T, McMahon C, Edwin D, Jarvis J, Cheverud J, Minn M . Identification of candidate alkylator-induced cancer susceptibility genes by whole genome scanning in mice. Cancer Res. 2006; 66(10):5029-38. DOI: 10.1158/0008-5472.CAN-05-3404. View