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Prediction of Thrombolytic Efficacy in Acute Ischemic Stroke Using Thin-section Noncontrast CT

Overview
Journal Neurology
Specialty Neurology
Date 2006 Nov 30
PMID 17130421
Citations 36
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Abstract

Thin-section noncontrast CT (NCT) can detect thrombi in large arteries and can provide a measure of thrombus composition based on Hounsfield Units (HU). A study using polyethylene tubes as a model of intracranial arteries concluded that the HUs of platelet-rich thrombi are lower than those of erythrocyte-rich thrombi. Thrombus HUs were measured by NCT in 34 patients with acute ischemic stroke before thrombolysis. Thrombi with lower HU counts were resistant to thrombolytics.

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