Pediatric Arteriovenous Malformation: University of Toronto Experience Using Stereotactic Radiosurgery

Overview

Journal Childs Nerv Syst

Specialty Pediatrics

Date 2006 Nov 23

PMID 17115227

Authors

Gelareh Zadeh

Yuri M Andrade-Souza

May N Tsao

Daryl Scora

Derek Armstrong

Robin Humphreys

James Rutka

James Drake

Peter Dirks

Michael L Schwartz

Affiliations

Soon will be listed here.

Abstract

Introduction And Background: Arteriovenous malformations (AVMs) are congenital vascular lesions of the brain, which behave differently in pediatric population compared to adults. Treatment of pediatric AVMs includes a combination of microsurgery, embolization and radiation therapies. However, the role of radiosurgery in the treatment of pediatric AVMs is not fully accepted because of concerns regarding the long-term effects of radiation on the pediatric brain.

Discussion: In this study, we review our experience at the University of Toronto with treating pediatric AVMs using linear accelerator-based (LINAC) radiosurgery over the past 15 years. We report our results, obliteration rates, and complications on a total of 40 patients. In addition, we provide a review of series published to date combined with our own results to determine whether radiosurgery is a safe and reasonable treatment modality for pediatric AVMs.

Citing Articles

Pediatric cranial stereotactic radiosurgery: Meta-analysis and international stereotactic radiosurgery society practice guidelines.

Murphy E, Sahgal A, Regis J, Levivier M, Fariselli L, Gorgulho A Neuro Oncol. 2024; 27(2):517-532.

PMID: 39390948 PMC: 11812027. DOI: 10.1093/neuonc/noae204.

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