Influence of Epicardial Adipose Tissue and Adipocytokine Levels on Cardiac Abnormalities in Visceral Obesity

Overview

Journal Int J Cardiol

Publisher Elsevier

Specialty Cardiology & Vascular Diseases

Date 2006 Nov 17

PMID 17107724

Citations 33

Authors

Alexis E Malavazos

Federica Ermetici

Calin Coman

Massimiliano M Corsi

Lelio Morricone

Bruno Ambrosi

Affiliations

Soon will be listed here.

Abstract

Adipocytokine levels and visceral adipose tissue (VAT) seem to be associated with some cardiac abnormalities and a role of visceral fat in predisposing to cardiac dysfunction, possibly through a low-grade state of inflammation, has been demonstrated. In this study we firstly show that elevated levels of both monocyte chemoattractant protein 1 (MCP-1) and soluble IL-6 receptor/interleukin-6 (sIL-6R/IL-6) complex are closely correlated with epicardial fat thickness.

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The density of crown-like structures in epicardial adipose tissue could play a role in cardiovascular diseases.

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