Exercise-induced Pulmonary Hemorrhage After Running a Marathon

Overview

Journal Lung

Specialty Pulmonary Medicine

Date 2006 Nov 7

PMID 17086462

Citations 9

Authors

Andrew J Ghio

Christine Ghio

Maryann Bassett

Affiliations

Soon will be listed here.

Abstract

We report on a healthy 26-year-old male who had an exercise-induced pulmonary hemorrhage (EIPH) within 24 hours of running a marathon. There were no symptoms, abnormalities on exam, or radiographic infiltrates. He routinely participated in bronchoscopy research and the EIPH was evident on gross inspection of bronchoalveolar lavage fluid, examination of the cytospin, and measurement of hemoglobin, iron, and ferritin concentrations. EIPH in humans may occur without any evidence on clinical presentation; its incidence may be far greater than currently suspected.

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References

Hopkins S, Gavin T, Siafakas N, Haseler L, Olfert I, Wagner H . Effect of prolonged, heavy exercise on pulmonary gas exchange in athletes. J Appl Physiol (1985). 1998; 85(4):1523-32. DOI: 10.1152/jappl.1998.85.4.1523. View

Dempsey J, Wagner P . Exercise-induced arterial hypoxemia. J Appl Physiol (1985). 1999; 87(6):1997-2006. DOI: 10.1152/jappl.1999.87.6.1997. View

Hopkins S, Schoene R, Henderson W, Spragg R, Martin T, West J . Intense exercise impairs the integrity of the pulmonary blood-gas barrier in elite athletes. Am J Respir Crit Care Med. 1997; 155(3):1090-4. DOI: 10.1164/ajrccm.155.3.9116992. View

Weiler-Ravell D, Shupak A, Goldenberg I, Halpern P, Shoshani O, Hirschhorn G . Pulmonary oedema and haemoptysis induced by strenuous swimming. BMJ. 1995; 311(7001):361-2. PMC: 2550430. DOI: 10.1136/bmj.311.7001.361. View

MCKECHNIE J, Leary W, Noakes T, Kallmeyer J, MacSearraigh E, Olivier L . Acute pulmonary oedema in two athletes during a 90-km running race. S Afr Med J. 1979; 56(7):261-5. View