Physical Map of the BK Virus Genome

Overview

Journal J Virol

Publisher American Society for Microbiology

Date 1975 Oct 1

PMID 170425

Citations 39

Authors

P M Howley

G Khoury

J C Byrne

K K Takemoto

M A Martin

Affiliations

Soon will be listed here.

Abstract

Two new human papovavirus isolates (JMV and MMV) from the urines of patients with Wiskott-Aldrich syndrome were morphologically and serologically identical to BK virus (BKV). The genomes of these two new isolates were found to be indistinguishable from prototype BKV DNA in a variety of nucleic acid hybridization experiments. Like BKV DNA, JMV and MMV DNAs share approximately 20% of their polynucleotide sequences with simian virus 40 DNA. The genome of JMV was indistinguishable from that of BKV by restriction endonuclease analysis; MMV DNA contained three instead of four R-Hind cleavage sites and one rather than no R-HpaII cleavage sites. Physical maps of the BKV and MMV genomes were constructed using restriction endonucleases, and these maps were oriented to the map of simian virus 40 DNA.

Citing Articles

Evolution of BK virus based on complete genome data.

Nishimoto Y, Takasaka T, Hasegawa M, Zheng H, Chen Q, Sugimoto C J Mol Evol. 2006; 63(3):341-52.

PMID: 16897259 DOI: 10.1007/s00239-005-0092-5.

Change of DNA near the origin of replication enhances the transforming capacity of human papovavirus BK.

Watanabe S, Yoshiike K J Virol. 1982; 42(3):978-85.

PMID: 6285007 PMC: 256931. DOI: 10.1128/JVI.42.3.978-985.1982.

BK virus-transformed inbred hamster brain cells. I. Status of the viral DNA and the association of BK virus early antigens with purified plasma membranes.

BETH E, Giraldo G, Schmidt-Ullrich R, Pater M, PATER A, DI MAYORCA G J Virol. 1981; 40(1):276-84.

PMID: 6270380 PMC: 256617. DOI: 10.1128/JVI.40.1.276-284.1981.

Organization of viral genome in a T antigen-negative hamster tumor induced by human papovavirus BK.

Yogo Y, Furuno A, Nozawa A, Uchida S J Virol. 1981; 38(2):556-63.

PMID: 6264127 PMC: 171186. DOI: 10.1128/JVI.38.2.556-563.1981.

Analysis of BK virus-transformed cells and BK virus-induced tumors by DNA-DNA reassociation kinetics.

Grossi M, Corallini A, Poli F, Valieri A, Milanesi G, Barbanti-Brodano G Arch Virol. 1981; 67(4):345-54.

PMID: 6263230 DOI: 10.1007/BF01314838.

References

Gardner S . Prevalence in England of antibody to human polyomavirus (B.k.). Br Med J. 2010; 1(5845):77-8. PMC: 1588750. DOI: 10.1136/bmj.1.5845.77. View

Howley P, Mullarkey M, Takemoto K, Martin M . Characterization of human papovavirus BK DNA. J Virol. 1975; 15(1):173-81. PMC: 354432. DOI: 10.1128/JVI.15.1.173-181.1975. View

Gatti R, GOOD R . Occurrence of malignancy in immunodeficiency diseases. A literature review. Cancer. 1971; 28(1):89-98. DOI: 10.1002/1097-0142(197107)28:1<89::aid-cncr2820280117>3.0.co;2-q. View

Shah K, Daniel R, Warszawski R . High prevalence of antibodies to BK virus, an SV40-related papovavirus, in residents of Maryland. J Infect Dis. 1973; 128(6):784-7. DOI: 10.1093/infdis/128.6.784. View

Pettersson U, Mulder C, Deluis H, Sharp P . Cleavage of adenovirus type 2 DNA into six unique fragments by endonuclease R-RI. Proc Natl Acad Sci U S A. 1973; 70(1):200-4. PMC: 433215. DOI: 10.1073/pnas.70.1.200. View

Sharp P, Pettersson U, Sambrook J . Viral DNA in transformed cells. I. A study of the sequences of adenovirus 2 DNA in a line of transformed rat cells using specific fragments of the viral genome. J Mol Biol. 1974; 86(4):709-26. DOI: 10.1016/0022-2836(74)90348-9. View

Mantyjarvi R, MEURMAN O, VIHMA L, Berglund B . A human papovavirus (B.K.), biological properties and seroepidemiology. Ann Clin Res. 1973; 5(5):283-7. View

Mullarkey M, Hruska J, Takemoto K . Comparison of two human papovaviruses with simian virus 40 by structural protein and antigenic analysis. J Virol. 1974; 13(5):1014-9. PMC: 355409. DOI: 10.1128/JVI.13.5.1014-1019.1974. View

Osborn J, Robertson S, PADGETT B, ZURHEIN G, Walker D, Weisblum B . Comparison of JC and BK human papovaviruses with simian virus 40: restriction endonuclease digestion and gel electrophoresis of resultant fragments. J Virol. 1974; 13(3):614-22. PMC: 355346. DOI: 10.1128/JVI.13.3.614-622.1974. View

10.

Major E, DI MAYORCA G . Malignant transformation of BHK21 clone 13 cells by BK virus--a human papovavirus. Proc Natl Acad Sci U S A. 1973; 70(11):3210-2. PMC: 427202. DOI: 10.1073/pnas.70.11.3210. View

11.

Takemoto K, Mullarkey M . Human papovavirus, BK strain: biological studies including antigenic relationship to simian virus 40. J Virol. 1973; 12(3):625-31. PMC: 356671. DOI: 10.1128/JVI.12.3.625-631.1973. View

12.

Danna K, Sack Jr G, Nathans D . Studies of simian virus 40 DNA. VII. A cleavage map of the SV40 genome. J Mol Biol. 1973; 78(2):363-76. DOI: 10.1016/0022-2836(73)90122-8. View

13.

Sharp P, Sugden B, Sambrook J . Detection of two restriction endonuclease activities in Haemophilus parainfluenzae using analytical agarose--ethidium bromide electrophoresis. Biochemistry. 1973; 12(16):3055-63. DOI: 10.1021/bi00740a018. View

14.

Sack Jr G, Narayan O, Danna K, Weiner L, Nathans D . The nucleic acid of an SV40-like virus isolated from a patient with progressive multifocal leukoencephalopathy. Virology. 1973; 51(2):345-50. DOI: 10.1016/0042-6822(73)90433-9. View

15.

Fareed G, Garon G, Salzman N . Origin and direction of simian virus 40 deoxyribonucleic acid replication. J Virol. 1972; 10(3):484-91. PMC: 356490. DOI: 10.1128/JVI.10.3.484-491.1972. View

16.

Nathans D, Danna K . Studies of SV40 DNA. 3. Differences in DNA from various strains of SV40. J Mol Biol. 1972; 64(2):515-8. DOI: 10.1016/0022-2836(72)90515-3. View

17.

Gelb L, Kohne D, Martin M . Quantitation of Simian virus 40 sequences in African green monkey, mouse and virus-transformed cell genomes. J Mol Biol. 1971; 57(1):129-45. DOI: 10.1016/0022-2836(71)90123-9. View

18.

Hirt B . Selective extraction of polyoma DNA from infected mouse cell cultures. J Mol Biol. 1967; 26(2):365-9. DOI: 10.1016/0022-2836(67)90307-5. View

19.

Takemoto K, Rabson A, Mullarkey M, Blaese R, Garon C, Nelson D . Isolation of papovavirus from brain tumor and urine of a patient with Wiskott-Aldrich syndrome. J Natl Cancer Inst. 1974; 53(5):1205-7. DOI: 10.1093/jnci/53.5.1205. View

20.

Blaese R, Strober W, Brown R, Waldmann T . The Wiskott-Aldrich syndrome. A disorder with a possible defect in antigen processing or recognition. Lancet. 1968; 1(7551):1056-61. DOI: 10.1016/s0140-6736(68)91411-6. View