A Web-based System for Tissue Microarray Data Management

Overview

Journal Diagn Pathol

Publisher Biomed Central

Specialty Pathology

Date 2006 Oct 13

PMID 17034635

Citations 4

Authors

Vincenzo Della Mea

Irene Bin

Maura Pandolfi

Carla Di Loreto

Affiliations

Soon will be listed here.

Abstract

Background: Tissue Microarray is a novel technique for analysing large amounts of immunohistochemically stained specimens. However, those large amounts make it difficult to design, prepare and analyze a tissue microarray, so that software support is almost inevitable.

Methods: We designed a tissue microarray data management system starting from specifications obtained by pathologists, and arranged for a preliminary validation in thyroid pathology.

Results: A web-based system has been developed, basing on open-source software and principles, that was well accepted by pathologists and allowed to carry out a study on 52 thyroid pathology cases.

Conclusion: Though limited in functionalities, the developed system is effective and can be downloaded at the address http://mitel.dimi.uniud.it/timan/.

Citing Articles

PATMA: parser of archival tissue microarray.

Roszkowiak L, Lopez C PeerJ. 2016; 4:e2741.

PMID: 27920955 PMC: 5136132. DOI: 10.7717/peerj.2741.

Datamining approach for automation of diagnosis of breast cancer in immunohistochemically stained tissue microarray images.

Prasad K, Zimmermann B, Prabhu G, Pai M Open Med Inform J. 2011; 4:86-93.

PMID: 21589855 PMC: 3095117. DOI: 10.2174/1874431101004010086.

Flow cytometric immunophenotyping (FCI) of lymphoma: correlation with histopathology and immunohistochemistry.

El-Sayed A, El-Borai M, Bahnassy A, El-Gerzawi S Diagn Pathol. 2008; 3:43.

PMID: 18986555 PMC: 2637251. DOI: 10.1186/1746-1596-3-43.

Ontology-based, Tissue MicroArray oriented, image centered tissue bank.

Viti F, Merelli I, Caprera A, Lazzari B, Stella A, Milanesi L BMC Bioinformatics. 2008; 9 Suppl 4:S4.

PMID: 18460177 PMC: 2367631. DOI: 10.1186/1471-2105-9-S4-S4.

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