The Effect on Creatinine Kinase Activity of Freezing Plasma from Healthy Foals

Aim: To assess the stability of creatine kinase (CK) activity in plasma collected from healthy foals and frozen at -20 degrees C for up to 12 weeks.

Methods: Samples of venous blood drawn from 25 foals were analysed for CK activity soon after collection, and again after 1 and 12 weeks of freezing at -20 degrees C.

Results: CK activity decreased (p<0.001) between Week 0 and Week 1 and between Week 0 and Week 12.

Conclusions And Clinical Relevance: Decreases in CK activity were statistically significant but clinically insignificant.