Tramadol Today

Overview

Journal Curr Opin Anaesthesiol

Specialty Anesthesiology

Date 2006 Oct 4

PMID 17016341

Citations 11

Authors

P J Le Roux

J F Coetzee

Affiliations

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Abstract

Tramadol is a unique analgesic offering moderate, dose-related pain relief through its action at multiple sites. In contrast to pure opioid agonists, it has a low risk of respiratory depression, tolerance and dependence. Troublesome side-effects have been reported, but tramadol has been established as an adjunct to non-steroidal anti-inflammatory drugs in the treatment of moderate postoperative pain and to abolish shivering. It may have advantages in paediatric and day-case surgery and as an adjunct in local anaesthetic techniques. This review provides an evidence-based account of the role of tramadol in modern practice.

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