Cd Exposures in Fathead Minnows: Effects on Adult Spawning Success and Reproductive Physiology

Overview

Journal Arch Environ Contam Toxicol

Specialty Environmental Health

Date 2006 Sep 30

PMID 17009127

Citations 4

Authors

Marlo K Sellin

Alan S Kolok

Affiliations

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Abstract

The primary objective of this study was to determine whether cadmium (Cd) exposures alter reproduction in fathead minnows (Pimephales promelas). Pairs of sexually mature minnows were exposed to waterborne Cd at 0, 12.5, 25, or 50 microg/L for 21 days. During this exposure period, the reproductive success of pairs was assessed. Following the exposure, gonadosomatic index (GSI), male secondary sexual characteristics, male plasma 11-ketotestosterone (11-KT) concentrations, and female plasma estradiol (E2) concentrations were determined. Results of this study show that Cd exposures impair reproduction in fathead minnows. Pairs exposed to 50 microg/L experienced a significant decline in spawning frequency and fecundity relative to unexposed minnows. Cd exposures also caused alterations in male secondary sexual characteristics, as males exposed to 25 microg/L had significantly fewer nuptial tubercles than controls. Furthermore, males exposed to 12.5 microg/L Cd experienced a significant increase in plasma 11-KT concentrations relative to controls. No alterations in GSI or female plasma E2 concentrations were observed.

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References

Sellin M, Kolok A . Cadmium exposures during early development: do they lead to reproductive impairment in fathead minnows?. Environ Toxicol Chem. 2006; 25(11):2957-63. PMC: 2763182. DOI: 10.1897/05-559r1.1. View

Migliarini B, Campisi A, Maradonna F, Truzzi C, Annibaldi A, Scarponi G . Effects of cadmium exposure on testis apoptosis in the marine teleost Gobius niger. Gen Comp Endocrinol. 2005; 142(1-2):241-7. DOI: 10.1016/j.ygcen.2004.12.012. View

Ankley G, Jensen K, Kahl M, Korte J, Makynen E . Description and evaluation of a short-term reproduction test with the fathead minnow (Pimephales promelas). Environ Toxicol Chem. 2001; 20(6):1276-90. View

Laberge F, HARA T . Neurobiology of fish olfaction: a review. Brain Res Brain Res Rev. 2001; 36(1):46-59. DOI: 10.1016/s0165-0173(01)00064-9. View

Foran C, Peterson B, Benson W . Influence of parental and developmental cadmium exposure on endocrine and reproductive function in Japanese medaka (Oryzias latipes). Comp Biochem Physiol C Toxicol Pharmacol. 2002; 133(3):345-54. DOI: 10.1016/s1532-0456(02)00128-x. View

Sloman K, Baker D, Ho C, McDonald D, Wood C . The effects of trace metal exposure on agonistic encounters in juvenile rainbow trout, Oncorhynchus mykiss. Aquat Toxicol. 2003; 63(2):187-96. DOI: 10.1016/s0166-445x(02)00176-5. View

Scott G, Sloman K, Rouleau C, Wood C . Cadmium disrupts behavioural and physiological responses to alarm substance in juvenile rainbow trout (Oncorhynchus mykiss). J Exp Biol. 2003; 206(Pt 11):1779-90. DOI: 10.1242/jeb.00353. View

Sloman K, Scott G, Diao Z, Rouleau C, Wood C, McDonald D . Cadmium affects the social behaviour of rainbow trout, Oncorhynchus mykiss. Aquat Toxicol. 2003; 65(2):171-85. DOI: 10.1016/s0166-445x(03)00122-x. View

Tilton S, Foran C, Benson W . Effects of cadmium on the reproductive axis of Japanese medaka (Oryzias latipes). Comp Biochem Physiol C Toxicol Pharmacol. 2003; 136(3):265-76. DOI: 10.1016/j.cca.2003.09.009. View

10.

Peake E, Locke J, Tierney L, Kolok A . Copper tolerance in fathead minnows: II. Maternal transfer. Environ Toxicol Chem. 2004; 23(1):208-11. PMC: 2698801. DOI: 10.1897/02-610. View

11.

Orlando E, Kolok A, Binzcik G, Gates J, Horton M, Lambright C . Endocrine-disrupting effects of cattle feedlot effluent on an aquatic sentinel species, the fathead minnow. Environ Health Perspect. 2004; 112(3):353-8. PMC: 1241866. DOI: 10.1289/ehp.6591. View

12.

Keitt S, Fagan T, Marts S . Understanding sex differences in environmental health: a thought leaders' roundtable. Environ Health Perspect. 2004; 112(5):604-9. PMC: 1241928. DOI: 10.1289/ehp.6714. View

13.

Henson M, Chedrese P . Endocrine disruption by cadmium, a common environmental toxicant with paradoxical effects on reproduction. Exp Biol Med (Maywood). 2004; 229(5):383-92. DOI: 10.1177/153537020422900506. View

14.

Brion F, Tyler C, Palazzi X, Laillet B, Porcher J, Garric J . Impacts of 17beta-estradiol, including environmentally relevant concentrations, on reproduction after exposure during embryo-larval-, juvenile- and adult-life stages in zebrafish (Danio rerio). Aquat Toxicol. 2004; 68(3):193-217. DOI: 10.1016/j.aquatox.2004.01.022. View

15.

Middaugh D, Dean J . Comparative sensitivity of eggs, larvae and adults of the estuarine teleosts, Fundulus heteroclitus and Menidia menidia to cadmium. Bull Environ Contam Toxicol. 1977; 17(6):645-52. DOI: 10.1007/BF01685947. View

16.

Hatakeyama S, Yasuno M . Chronic effects of Cd on the reproduction of the guppy (Poecilia reticulata) through Cd-accumulated midge larvae (Chironomus yoshimatsui). Ecotoxicol Environ Saf. 1987; 14(3):191-207. DOI: 10.1016/0147-6513(87)90062-5. View

17.

Vetillard A, Bailhache T . Cadmium: an endocrine disrupter that affects gene expression in the liver and brain of juvenile rainbow trout. Biol Reprod. 2004; 72(1):119-26. DOI: 10.1095/biolreprod.104.029520. View

18.

Nichols K, Snyder E, Snyder S, Pierens S, Giesy J . Effects of nonylphenol ethoxylate exposure on reproductive output and bioindicators of environmental estrogen exposure in fathead minnows Pimephales promelas. Environ Toxicol Chem. 2001; 20(3):510-22. DOI: 10.1897/1551-5028(2001)020<0510:eoneeo>2.0.co;2. View