Prevention of Membrane Damage in Patient on Peritoneal Dialysis with New Peritoneal Dialysis Solutions

Overview

Journal Int Urol Nephrol

Publisher Springer

Specialty Nephrology

Date 2006 Sep 28

PMID 17004033

Citations 6

Authors

Mufazzal Ahmad

Hemal Shah

Theodori Pliakogiannis

Dimitrios G Oreopoulos

Affiliations

Soon will be listed here.

Abstract

Peritoneal dialysis (PD) is now an established and successful alternative to hemodialysis. Multiple studies have confirmed its equivalent dialysis adequacy, mortality and fluid balance status, at least for the first 4-5 years. Peritoneal membrane failure is now one of the leading cause of technique failure. This review describes the role of glucose, glucose degradation product, pH, lactate, advanced glycosylation end product (AGE) in causing this membrane damage, and gives insight how the use of newer peritoneal dialysis fluids (PDFs) containing icodextrin, amino acids and bicarbonate buffer can prevent peritoneal membrane damage.

Citing Articles

Role of miRNA-21/PTEN on the high glucose-induced EMT in human mesothelial peritoneal cells.

Yang L, Fan Y, Zhang X, Gao L, Ma J Am J Transl Res. 2018; 10(8):2590-2599.

PMID: 30210695 PMC: 6129511.

Two icodextrin exchanges per day in peritoneal dialysis patients with ultrafiltration failure: one center's experience and review of the literature.

Dousdampanis P, Trigka K, Chu M, Khan S, Venturoli D, Oreopoulos D Int Urol Nephrol. 2010; 43(1):203-9.

PMID: 20953705 DOI: 10.1007/s11255-010-9716-9.

No need for an "expiry date" in chronic peritoneal dialysis to prevent encapsulating peritoneal sclerosis.

Garosi G, Oreopoulos D Int Urol Nephrol. 2009; 41(4):903-7.

PMID: 19856126 DOI: 10.1007/s11255-009-9661-7.

Prolonged use of the tyrosine kinase inhibitor in a peritoneal dialysis patient with metastatic renal cell carcinoma: possible beneficial effects on peritoneal membrane and peritonitis rates.

Tapiawala S, Bargman J, Oreopoulos D, Simons M Int Urol Nephrol. 2009; 41(2):431-4.

PMID: 19255867 DOI: 10.1007/s11255-009-9545-x.

The promising future of long-term peritoneal dialysis.

Oreopoulos D, Thodis E, Paraskevas K Int Urol Nephrol. 2008; 40(2):405-10.

PMID: 18368504 DOI: 10.1007/s11255-008-9370-7.

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