Back to the Future: Education for Systems-level Biologists
Overview
Molecular Biology
Authors
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We describe a graduate course in quantitative biology that is based on original path-breaking papers in diverse areas of biology; each of these papers depends on quantitative reasoning and theory as well as experiment. Close reading and discussion of these papers allows students with backgrounds in physics, computational sciences or biology to learn essential ideas and to communicate in the languages of disciplines other than their own.
Rethinking (again) Hardy-Weinberg and genetic drift in undergraduate biology.
Klymkowsky M Front Genet. 2023; 14:1199739.
PMID: 37359366 PMC: 10285527. DOI: 10.3389/fgene.2023.1199739.
Williams J, Drew J, Galindo-Gonzalez S, Robic S, Dinsdale E, Morgan W PLoS One. 2019; 14(11):e0224288.
PMID: 31738797 PMC: 6860448. DOI: 10.1371/journal.pone.0224288.
Friesner J, Assmann S, Bastow R, Bailey-Serres J, Beynon J, Brendel V Plant Physiol. 2017; 175(4):1499-1509.
PMID: 29208732 PMC: 5717721. DOI: 10.1104/pp.17.01490.
An engineering design approach to systems biology.
Janes K, Chandran P, Ford R, Lazzara M, Papin J, Peirce S Integr Biol (Camb). 2017; 9(7):574-583.
PMID: 28590470 PMC: 6534349. DOI: 10.1039/c7ib00014f.
Discovering New Biology through Sequencing of RNA.
Weber A Plant Physiol. 2015; 169(3):1524-31.
PMID: 26353759 PMC: 4634082. DOI: 10.1104/pp.15.01081.