Transcription Modulation of Salmonella Enterica Serovar Typhimurium Promoters by Sub-MIC Levels of Rifampin

Overview

Journal J Bacteriol

Publisher American Society for Microbiology

Specialty Microbiology

Date 2006 Sep 19

PMID 16980465

Citations 29

Authors

Grace Yim

Fernando de la Cruz

George B Spiegelman

Julian Davies

Affiliations

Soon will be listed here.

Abstract

Promoter-lux fusions that showed rifampin-modulated transcription were identified from a Salmonella enterica serovar Typhimurium 14028 reporter library. The transformation of a subset of fusions into mutants that lacked one of six global regulatory proteins or were rifampin resistant showed that transcription modulation was independent of the global regulators, promoter specific, and dependent on the interaction of rifampin with RNA polymerase.

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