A Breakdown in Macromolecular Synthesis Preceding Differentiation in Streptomyces Coelicolor A3(2)

Overview

Journal J Gen Microbiol

Specialty Microbiology

Date 1990 Apr 1

PMID 1697885

Citations 17

Authors

C Granozzi

R Billetta

R Passantino

M Sollazzo

A M Puglia

Affiliations

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Abstract

A transitory cessation of growth was recorded in Streptomyces coelicolor A3(2) at the end of vegetative mycelium formation on solid medium. In the same phase a striking reduction in protein and nucleic acid synthesis was detected. Growth and macromolecular synthesis resumed, nearly reaching the original values, when morphological differentiation occurred. It is concluded that a physiological stress occurs within the bacterial population just before the onset of the morphological differentiation.

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