Characterization of a Phenotypically Unique Population of CD13+ Dendritic Cells Resident in the Spleen

Overview

Journal Clin Vaccine Immunol

Publisher American Society for Microbiology

Specialties Allergy & Immunology
Pathology

Date 2006 Sep 9

PMID 16960120

Citations 4

Authors

Yan Zhuang

Waithaka Mwangi

Wendy C Brown

William C Davis

Jayne C Hope

Guy H Palmer

Affiliations

Soon will be listed here.

Abstract

Immature dendritic cells (DCs) resident in bovine spleens represent a distinct CD11a(+) CD11c(+) CD13(+) CD172(+) CD205(+) population compared to those circulating in peripheral blood or trafficking via afferent lymph. Upon cytokine-induced maturation, splenic DCs both efficiently present antigen in the stimulation of allogeneic lymphocyte proliferation and recall antigen-specific responses.

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