Lymphocyte Proliferation in Peyer's Patches of Giardia Muris-infected Mice

Overview

Journal Infect Immun

Publisher American Society for Microbiology

Specialty Allergy & Immunology

Date 1990 Aug 1

PMID 1695208

Citations 5

Authors

D R Hill

Affiliations

Soon will be listed here.

Abstract

Gastrointestinal immune events in giardiasis are important in controlling infection. In this study, Peyer's patch lymphocytes from mice infected with Giardia muris developed specific, proliferative responses to G. muris antigen. This proliferation correlated with clearance of infection. Further understanding of the gut immune response will be helpful in developing immunoprophylactic strategies in the control of giardiasis.

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References

Targan S, Kagnoff M, Brogan M, Shanahan F . Immunologic mechanisms in intestinal diseases. Ann Intern Med. 1987; 106(6):853-70. DOI: 10.7326/0003-4819-106-6-853. View

Underdown B, Skea D, Loney G, Snider D . Murine giardiasis and mucosal immunity: a model for the study of immunity to intestinal protozoan parasites. Monogr Allergy. 1988; 24:287-96. View

Carlson J, Heyworth M, Owen R . Response of Peyer's patch lymphocyte subsets to Giardia muris infection in BALB/c mice. II. B-cell subsets: enteric antigen exposure is associated with immunoglobulin isotype switching by Peyer's patch B cells. Cell Immunol. 1986; 97(1):51-8. DOI: 10.1016/0008-8749(86)90374-6. View

Snider D, Underdown B . Quantitative and temporal analyses of murine antibody response in serum and gut secretions to infection with Giardia muris. Infect Immun. 1986; 52(1):271-8. PMC: 262230. DOI: 10.1128/iai.52.1.271-278.1986. View

Roberts-Thomson I, Mitchell G . Giardiasis in mice. I. Prolonged infections in certain mouse strains and hypothymic (nude) mice. Gastroenterology. 1978; 75(1):42-6. View

Kawanishi H, Saltzman L, Strober W . Mechanisms regulating IgA class-specific immunoglobulin production in murine gut-associated lymphoid tissues. I. T cells derived from Peyer's patches that switch sIgM B cells to sIgA B cells in vitro. J Exp Med. 1983; 157(2):433-50. PMC: 2186919. DOI: 10.1084/jem.157.2.433. View

Kiyono H, Cooper M, Kearney J, Mosteller L, Michalek S, Koopman W . Isotype specificity of helper T cell clones. Peyer's patch Th cells preferentially collaborate with mature IgA B cells for IgA responses. J Exp Med. 1984; 159(3):798-811. PMC: 2187251. DOI: 10.1084/jem.159.3.798. View

TOMASI Jr T . Mechanisms of immune regulation at mucosal surfaces. Rev Infect Dis. 1983; 5 Suppl 4:S784-92. DOI: 10.1093/clinids/5.supplement_4.s784. View

Istre G, Dunlop T, Gaspard G, Hopkins R . Waterborne giardiasis at a mountain resort: evidence for acquired immunity. Am J Public Health. 1984; 74(6):602-4. PMC: 1651646. DOI: 10.2105/ajph.74.6.602. View

10.

Frangakis M, Koopman W, Kiyono H, Michalek S, McGhee J . An enzymatic method for preparation of dissociated murine Peyer's patch cells enriched for macrophages. J Immunol Methods. 1982; 48(1):33-44. DOI: 10.1016/0022-1759(82)90207-1. View

11.

Bienenstock J, Befus A . Mucosal immunology. Immunology. 1980; 41(2):249-70. PMC: 1458175. View

12.

Richman L, Graeff A, Strober W . Antigen presentation by macrophage-enriched cells from the mouse Peyer's patch. Cell Immunol. 1981; 62(1):110-8. DOI: 10.1016/0008-8749(81)90304-x. View

13.

Kiyono H, McGhee J, Wannemuehler M, Frangakis M, Spalding D, Michalek S . In vivo immune response to a T-cell-dependent antigen by cultures of disassociated murine Peyer's patch. Proc Natl Acad Sci U S A. 1982; 79(2):596-600. PMC: 345792. DOI: 10.1073/pnas.79.2.596. View

14.

MacDonald T, CARTER P . Isolation and functional characteristics of adherent phagocytic cells from mouse Peyer's patches. Immunology. 1982; 45(4):769-74. PMC: 1555428. View

15.

Owen R, Allen C, Stevens D . Phagocytosis of Giardia muris by macrophages in Peyer's patch epithelium in mice. Infect Immun. 1981; 33(2):591-601. PMC: 350740. DOI: 10.1128/iai.33.2.591-601.1981. View

16.

ANDREWS Jr J, Ellner J, Stevens D . Purification of Giardia muris trophozoites by using nylon fiber columns. Am J Trop Med Hyg. 1980; 29(1):12-5. DOI: 10.4269/ajtmh.1980.29.12. View

17.

Cebra J, Gearhart P, Kamat R, Robertson S, Tseng J . Origin and differentiation of lymphocytes involved in the secretory IgA responses. Cold Spring Harb Symp Quant Biol. 1977; 41 Pt 1:201-15. DOI: 10.1101/sqb.1977.041.01.026. View

18.

Duncombe V, Bolin T, Davis A, Cummins A, CROUCH R . Histopathology in giardiasis: a correlation with diarrhoea. Aust N Z J Med. 1978; 8(4):392-6. DOI: 10.1111/j.1445-5994.1978.tb04908.x. View

19.

Elson C, Heck J, Strober W . T-cell regulation of murine IgA synthesis. J Exp Med. 1979; 149(3):632-43. PMC: 2184830. DOI: 10.1084/jem.149.3.632. View

20.

Oyerinde J, Ogunbi O, Alonge A . Age and sex distribution of infections with Entamoeba histolytica and Giardia intestinalis in the Lagos population. Int J Epidemiol. 1977; 6(3):231-4. DOI: 10.1093/ije/6.3.231. View