Relevance of Weil-Felix Test in Diagnosis of Scrub Typhus in India

Overview

Journal J Assoc Physicians India

Specialty General Medicine

Date 2006 Sep 1

PMID 16941792

Citations 38

Authors

S K Mahajan

R Kashyap

A Kanga

V Sharma

B S Prasher

L S Pal

Affiliations

Soon will be listed here.

Abstract

Objective: To study the relationship of Weil-Felix test and microimmunofluorescence test.

Methods: Sera of 21 patients with clinical diagnosis of scrub typhus were subjected to Weil-Felix and Microimmunofluorescence tests.

Results: On Weil-Felix test, 13 (62%) sera showed titers 1: > or = 40-320. 7 patients showed titers 1: > or = 320, 3 showed titers 1 : 160, 2 showed titers 1 : 80 and 1 patients showed titers 1 : 40, to Proteus OXK antigen. All 21 sera showed significant titers to O. tsutsugamushi on microimmunofluorescence.

Conclusion: Weil-Felix test is not a very sensitive test in diagnosis of scrub typhus but due to of lack of availability of definitive tests in India it canbe a useful tool when used and interpreted in the correct clinical context.

Citing Articles

A Clinical Study of Rickettsial Fever and Factors Affecting Its Outcome.

Shivnitwar S, Rajput S, Avate A, Narayankar A, Sujanyal S, Ahlawat M Cureus. 2024; 16(7):e63747.

PMID: 39099995 PMC: 11296700. DOI: 10.7759/cureus.63747.

Post-fever Retinitis With a Positive Weil-Felix Test: A Study From a Tertiary Center in South India.

Wani V, Tenagi A, Bubanale S, B K B, Mutalik D, Warad C Cureus. 2024; 16(1):e53162.

PMID: 38420096 PMC: 10901253. DOI: 10.7759/cureus.53162.

Rickettsia africae and other unclassified Rickettsia species of the spotted fever group in ticks of the Western Ghats, India.

Babu N, Jayaram A, Auti A, Bhandari Y, Shetty U, Arunkumar G Exp Appl Acarol. 2023; 90(3-4):429-440.

PMID: 37347433 PMC: 10406665. DOI: 10.1007/s10493-023-00814-2.

Acute respiratory distress syndrome in Scrub typhus - An under recognized complication!.

Kamath S, Ahmed T, Kumar M, Sunder A J Family Med Prim Care. 2023; 12(1):165-167.

PMID: 37025215 PMC: 10071914. DOI: 10.4103/jfmpc.jfmpc_1130_22.

Neurological manifestations of scrub typhus infection: A systematic review and meta-analysis of clinical features and case fatality.

Alam A, Gillespie C, Goodall J, Damodar T, Turtle L, Vasanthapuram R PLoS Negl Trop Dis. 2022; 16(11):e0010952.

PMID: 36441812 PMC: 9731453. DOI: 10.1371/journal.pntd.0010952.