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Bioconductor: an Open Source Framework for Bioinformatics and Computational Biology

Overview
Journal Methods Enzymol
Specialty Biochemistry
Date 2006 Aug 31
PMID 16939789
Citations 122
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Abstract

This chapter describes the Bioconductor project and details of its open source facilities for analysis of microarray and other high-throughput biological experiments. Particular attention is paid to concepts of container and workflow design, connections of biological metadata to statistical analysis products, support for statistical quality assessment, and calibration of inference uncertainty measures when tens of thousands of simultaneous statistical tests are performed.

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