In Situ Hybridization

Overview

Journal Clin Lab Med

Specialty Pathology

Date 1990 Mar 1

PMID 1691963

Citations 8

Authors

M H Stoler

Affiliations

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Abstract

In situ hybridization is a technique with wide application in laboratory medicine. In this article, the basic and technical aspects of in situ hybridization are reviewed, and applications are discussed that emphasize methods for the detection of gene expression.

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Double fluorescence in situ hybridization in fresh brain sections.

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Concomitant oncoprotein detection with fluorescence in situ hybridization (CODFISH): a fluorescence-based assay enabling simultaneous visualization of gene amplification and encoded protein expression.

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Fixation conditions for DNA and RNA in situ hybridization: a reassessment of molecular morphology dogma.

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The intracellular localization of human cytomegalovirus DNA in peripheral blood leukocytes during active infections by high-resolution fluorescence in situ hybridization.

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