In Vitro Bactericidal Activities of Japanese Rice-fluid Against Helicobacter Pylori Strains

Overview

Journal Int J Med Sci

Specialty General Medicine

Date 2006 Aug 15

PMID 16906220

Citations 4

Authors

Yoshiyuki Kawakami

Kozue Oana

Masayoshi Hayama

Hiroyoshi Ota

Masahiko Takeuchi

Kazuhiro Miyashita

Tsunetomo Matsuzawa

Kiyomi Kanaya

Affiliations

Soon will be listed here.

Abstract

Background: Helicobacter pylori has now been widely recognized as a causative agent of gastroduodenal diseases. The development of safer anti- H. pylori compounds is desirable due to the antibiotic-resistant strains emerged to date.

Methods: We successfully developed the compounds of Rice-fluid derived from unpolished, polished, and usually cooked Japanese rice, and investigated their in vitro antibacterial activities by means of the Time-Kill-Curve methods against various species of bacteria including H. pylori strains.

Results: All of the compounds revealed keen bactericidal activities against H. pylori, followed by Streptococcus pneumoniae and Campylobacter jejuni strains, but failed to affect the viability of other bacterial species investigated including staphylococci, enterococci, Pseudomonas aeruginosa, and other gram-negative rods belonging to the family Enterobacteraceae. The bactericidal activities were demonstrated to be time- and concentration-dependent.

Conclusions: The compounds of Rice-fluid are considered to be potentially new and safe therapeutic regimens against H. pylori infections. The mechanism of their bactericidal activities against H. pylori strains remains to be elucidated.

Citing Articles

Anti-Helicobacter pylori activity of nanocomposites from chitosan/broccoli mucilage/selenium nanoparticles.

Aborabu A, Tayel A, Assas M, Moussa S, Alalawy A, Almutairi F Sci Rep. 2024; 14(1):21693.

PMID: 39289449 PMC: 11408496. DOI: 10.1038/s41598-024-65762-2.

Antitumor properties of two traditional aromatic rice genotypes (Kalijira and Chinigura).

Mannan M, Sarker T, Kabir A, Rahman M, Alam M Avicenna J Phytomed. 2014; 4(1):31-42.

PMID: 25050299 PMC: 4103728.

Scientific evaluation of edible fruits and spices used for the treatment of peptic ulcer in traditional Iranian medicine.

Farzaei M, Shams-Ardekani M, Abbasabadi Z, Rahimi R ISRN Gastroenterol. 2013; 2013:136932.

PMID: 24066235 PMC: 3770045. DOI: 10.1155/2013/136932.

In vivo bactericidal activities of Japanese rice-fluid against H. pylori in a Mongolian gerbil model.

Ishizone S, Maruta F, Suzuki K, Miyagawa S, Takeuchi M, Kanaya K Int J Med Sci. 2007; 4(4):203-8.

PMID: 17717596 PMC: 1950273. DOI: 10.7150/ijms.4.203.

References

Funatogawa K, Hayashi S, Shimomura H, Yoshida T, Hatano T, Ito H . Antibacterial activity of hydrolyzable tannins derived from medicinal plants against Helicobacter pylori. Microbiol Immunol. 2004; 48(4):251-61. DOI: 10.1111/j.1348-0421.2004.tb03521.x. View

Shibata K, Kasuga O, Yasoshima A, Matsushita T, Kawakami Y . Bactericidal effect of ecabet sodium on clarithromycin- and metronidazole-resistant clinical isolates of Helicobacter pylori. Jpn J Antibiot. 1997; 50(6):525-31. View

Asaka M, Sugiyama T, Kato M, Satoh K, Kuwayama H, Fukuda Y . A multicenter, double-blind study on triple therapy with lansoprazole, amoxicillin and clarithromycin for eradication of Helicobacter pylori in Japanese peptic ulcer patients. Helicobacter. 2001; 6(3):254-61. DOI: 10.1046/j.1523-5378.2001.00037.x. View

Shimizu T, Akamatsu T, Sugiyama A, Ota H, Katsuyama T . Helicobacter pylori and the surface mucous gel layer of the human stomach. Helicobacter. 1996; 1(4):207-18. DOI: 10.1111/j.1523-5378.1996.tb00041.x. View

Kawakami Y, Akahane T, Gotoh A, Okimura Y, Oana K, Katsuyama T . Successful development of air-dried microplates (HP-Plates) for susceptibility testing against Helicobacter pylori isolates. Microbiol Immunol. 1997; 41(9):703-8. DOI: 10.1111/j.1348-0421.1997.tb01914.x. View

OConnor H, Kanduru C, Bhutta A, Meehan J, Feeley K, Cunnane K . Effect of Helicobacter pylori eradication on peptic ulcer healing. Postgrad Med J. 1995; 71(832):90-3. PMC: 2397943. DOI: 10.1136/pgmj.71.832.90. View

Sipponen P . Gastric cancer--a long-term consequence of Helicobacter pylori infection?. Scand J Gastroenterol Suppl. 1994; 201:24-7. View

Gotoh A, Kawakami Y, Akamatsu T, Katsuyama T . Interaction of drugs for eradication therapy against antibiotic-resistant strains of Helicobacter pylori. Microbiol Immunol. 1997; 41(11):865-9. DOI: 10.1111/j.1348-0421.1997.tb01942.x. View

Hayama M, Kawakami Y, Kaneko Y, Sano K, Ota H . Helicobacter pylori infection increases cell kinetics in human gastric epithelial cells without adhering to proliferating cells. J Cell Mol Med. 2005; 9(3):746-7. PMC: 6741418. DOI: 10.1111/j.1582-4934.2005.tb00508.x. View

10.

Dixon M . Helicobacter pylori and peptic ulceration: histopathological aspects. J Gastroenterol Hepatol. 1991; 6(2):125-30. DOI: 10.1111/j.1440-1746.1991.tb01451.x. View

11.

Kawakami Y, Akahane T, Yamaguchi M, Oana K, Takahashi Y, Okimura Y . In vitro activities of rabeprazole, a novel proton pump inhibitor, and its thioether derivative alone and in combination with other antimicrobials against recent clinical isolates of Helicobacter pylori. Antimicrob Agents Chemother. 2000; 44(2):458-61. PMC: 89707. DOI: 10.1128/AAC.44.2.458-461.2000. View

12.

Kawakami Y . [Antimicrobial susceptibilities of Helicobacter pylori isolates and its clinical significance in chemotherapy]. Rinsho Biseibutshu Jinsoku Shindan Kenkyukai Shi. 2001; 11(2):69-77. View

13.

Uemura N, Mukai T, Okamoto S, Yamaguchi S, Mashiba H, Taniyama K . Effect of Helicobacter pylori eradication on subsequent development of cancer after endoscopic resection of early gastric cancer. Cancer Epidemiol Biomarkers Prev. 1997; 6(8):639-42. View

14.

Weber D, Dimopoulos M, Anandu D, Pugh W, Steinbach G . Regression of gastric lymphoma of mucosa-associated lymphoid tissue with antibiotic therapy for Helicobacter pylori. Gastroenterology. 1994; 107(6):1835-8. DOI: 10.1016/0016-5085(94)90828-1. View

15.

Wotherspoon A, Doglioni C, Diss T, Pan L, Moschini A, de Boni M . Regression of primary low-grade B-cell gastric lymphoma of mucosa-associated lymphoid tissue type after eradication of Helicobacter pylori. Lancet. 1993; 342(8871):575-7. DOI: 10.1016/0140-6736(93)91409-f. View

16.

. Current European concepts in the management of Helicobacter pylori infection. The Maastricht Consensus Report. European Helicobacter Pylori Study Group. Gut. 1997; 41(1):8-13. PMC: 1027220. DOI: 10.1136/gut.41.1.8. View

17.

Cowan M . Plant products as antimicrobial agents. Clin Microbiol Rev. 1999; 12(4):564-82. PMC: 88925. DOI: 10.1128/CMR.12.4.564. View

18.

Marshall B, Armstrong J, McGechie D, Glancy R . Attempt to fulfil Koch's postulates for pyloric Campylobacter. Med J Aust. 1985; 142(8):436-9. DOI: 10.5694/j.1326-5377.1985.tb113443.x. View

19.

Gotoh A, Akamatsu T, Shimizu T, Shimodaira K, Kaneko T, Kiyosawa K . Additive effect of pronase on the efficacy of eradication therapy against Helicobacter pylori. Helicobacter. 2002; 7(3):183-91. DOI: 10.1046/j.1523-5378.2002.00079.x. View

20.

Warren J, Marshall B . Unidentified curved bacilli on gastric epithelium in active chronic gastritis. Lancet. 1983; 1(8336):1273-5. View