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ACE Inhibition Can Improve Orthostatic Proteinuria Associated with Nutcracker Syndrome

Overview
Journal Pediatr Nephrol
Specialties Nephrology
Pediatrics
Date 2006 Aug 12
PMID 16902785
Citations 19
Authors
Tae-Sun Ha
Eun-Ju Lee
Affiliations
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Abstract

Left renal vein entrapment syndrome (nutcracker syndrome) was documented by magnetic resonance angiography (MRA) as a cause of orthostatic proteinuria in a 14-year-old girl female adolescent. Because of continuous proteinuria we performed a left renal biopsy which showed moderate mesangial hypercellularity. Her overt orthostatic proteinuria disappeared after a treatment of angiotensin-converting enzyme (ACE) inhibition. Nutcracker syndrome remains a rare but important cause of elevated protein excretion, which can induce mesangial changes and be improved by ACE inhibitor treatment.

Citing Articles

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Orthostatic proteinuria due to inferior vena cava interruption without nutcracker phenomenon in an old obese female: a case report and literature review.

Lin L, Zhang K, Yang X, Lin L, Li X, Qiu L BMC Nephrol. 2023; 24(1):225.

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